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Interleukin-6: Genetics, Clinical Applications and Role in Disease
Retail Price: $209.00
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Editors: Jovanni D'Aquino and Edward N. DeVito
Book Description:
Interleukin-6 (IL-6) is a pleiotropic cytokine that plays an important role in acute inflammation. It is secreted by T cells and macrophages during infection and after trauma. It is responsible for activation of B cells and other immune cells. In this book, the authors discuss the genetics, clinical applications and role in disease of interleukin-6. Topics include IL-6 inhibitors as novel generation of treatment strategies; the role of interleukin-6 in postoperative delirium; elevated interleukin-6 levels as a consequence of obesity and insulin resistance; the effects of IL-6 on respiratory mechanics in rats; and IL-6 targeting strategy for rheumatoid arthritis and various immune-mediated diseases. (Imprint: Nova Biomedical)

Please click on a chapter below to purchase separately

Chapter 1 - Interleukin-6 Inhibitors as Novel Generation of Treatment Strategies (pp. 1-60)
Authors / Editors: (Vaclav Liska, David Glanc, Ondrej Vycital, Jan Bruha, Pavel Pitule, Jana Kopalova, Richard Palek, Vladislav Treska, Department of Surgery, Biomedical Centre, and Institut of Histology and Embryology, Faculty of Medicine in Pilsen, Charles University in Prague, Czech Republic and others)

Chapter 2 - IL-6 Targeting Strategy for Various Immune-Mediated Diseases other than Rheumatoid Arthritis: An Update Review (pp. 61-110)
Authors / Editors: (Toshio Tanaka, Atsushi Ogata, Yoshihito Shima, Masashi Narazaki, Atsushi Kumanogoh, Tadamitsu Kishimoto, Department of Clinical Application of Biologics, Osaka University of Graduate)

Chapter 3 - IL-6 Targeting Strategy for Rheumatoid Arthritis (pp. 111-150)
Authors / Editors: (Atsushi Ogata, Yuji Yoshida, Atsuyoshi Morishima, Atsushi Kumanogoh and Toshio Tanaka, Department of Respiratory Medicine, Allergy and Rheumatic Diseases, and others) )
***Open Access Chapter. Free Download Available***

Chapter 4 - Role of Interleukin-6 in Cardiovascular Diseases (pp. 151-178)
Authors / Editors: (A.H.M. Nurun Nabi, Thomas J. Kuehl, Mohammad Nasir Uddin, Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka, Bangladesh and others)

Chapter 5 - Effects of IL-6 on Respiratory Mechanics in the Rat (pp. 151-178)
Authors / Editors: (Alessandro Rubini, Andrea Parmagnani, Department of Biomedical Sciences, Section Physiology, University of Padova, Padua, Italy)

Chapter 6 - Elevated Interlukin-6 Levels as a Consequence, not the Cause of Obesity and Insulin Resistance (pp. 179-196)
Authors / Editors: (Anna Benrick and Ingrid Wernstedt Asterholm, Institute of Neuroscience and Physiology, Department of Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden and others)

Chapter 7 - The Role of Interleukin-6 in Postoperative Delirium (pp. 197-218)
Authors / Editors: (Konstanze Plaschke, Department of Anesthesiology, Clinical-Experimental Anesthesiology, Medical Faculty of the University of Heidelberg, Germany)

      Protein Biochemistry, Synthesis, Structure and Cellular Functions
      Immunology and Immune System Disorders
   Binding: Hardcover
   Pub. Date: 2013- April
   Pages: 243, 7x10 - (NBC-R)
   ISBN: 978-1-62417-592-3
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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Interleukin-6: Genetics, Clinical Applications and Role in Disease