Editors: Sarah E. Gallagher |
Book Description: Beta cells or β-cells, are a type of cell in the pancreas in areas called the islets of Langerhans. They make up 65-80% of the cells in the islets. Pancreatic B-cell is the only cell type that produces insulin to regulate glucose metabolism in the body. The insufficiency of insulin-producing B-cells results in dysregulation of blood glucose control, termed as type 1 diabetes. This book presents current research from across the globe in the study of Beta-cells, including the induction of pancreatic cancer cell death by elevated concentrations of extracellular zinc; the role of Rab GTPases and their effectors in the insulin secretory pathway of the pancreatic beta cell; In vivo reprogramming of pancreatic A-cells into B-like cells; and the role of glucocortoids, exercise and glucolipotoxicity with regard to stress and pancreatic B-cell function.
(Imprint: Nova Biomedical)
We’ve partnered with Copyright Clearance Center to make it easy for you to request permissions to reuse Nova content.
For more information, click here or click the "Get Permission" button below to link directly to this book on Copyright Clearance Center's website.
 |
Please click on a chapter below to purchase separately |
Chapter 1 - Stress and Pancreatic β Cell Function: Role of Glucocortoids, Exercise and Glucolipotoxicity Authors / Editors: Jacqueline Beaudry, Michael Riddell, York University, Kinesiology and Health Science, Toronto, Ontario, Canada |
Chapter 2 - The Synergistic Effect of β Cell Replacement and Immunotherapy on the Treatment of Type 1 Diabetes Authors / Editors: Dong-Sheng Li, Garth L.Warnock, Hong Lu, Long-Jun Dai, Hubei Key Laboratory of Embryonic Stem Cell Research, Tai-He Hospital, Yunyang Medical College, Shiyan, Hubei, China, and others |
Chapter 3 - Antagonizing the Endocannabinoid Pathway Prevents the Development of Diabetes and β Cell Dysfunction in Zucker Diabetic Fatty Rats Authors / Editors: V. Duvivier, Ch. Duquenne, V. Delion, F. Petoux, J. Ludop-Maignel, Ph. Chamiot-Clerc, M.P. Pruniaux, A.M. Galzin, Sanofi-Aventis R&D, Discovery Research Metabolism Department, Rueil-Malmaison, France
***Open Access Chapter. Free Download Available*** |
Chapter 4 - Diabetes Mellitus: An Opportunity for Therapy with Regenerative Medicine? Authors / Editors: Akifumi Matsuyama, Department of Somatic Stem Cell Therapy and Health Policy, Foundation for Biomedical Research and Innovation, Kobe, Japan
***Open Access Chapter. Free Download Available*** |
Chapter 5 - Behind Beta Cell Glucotoxicity: A Pivotal Role of Glycoxidative Damage? Authors / Editors: Alessandra Puddu, Daniela Storace, Department of Internal Medicine and Medical Specialties (Di.M.I.), University of Genova, Italy |
Chapter 6 - Induction of Pancreatic Cancer Cell Death by Elevated Concentrations of Extracellular Zinc Authors / Editors: Sundararajan Jayaraman, Arathi K. Jayaraman, University of Illinois at Chicago, Illinois |
Chapter 7 - Rab GTPases Control Membrane Recycling in the Pancreatic Beta Cell Authors / Editors: Toshihide Kimura, Ichiro Niki, Department of Pharmacology, Oita University Faculty of Medicine at Oita, Japan
***Open Access Chapter. Free Download Available*** |
Chapter 8 - In Vivo Reprogramming of Pancreatic -cells into β-like Cells Authors / Editors: Ahmed Mansouri, Patrick Collombat, Max-Planck Institute for Biophysical Chemistry, Department of Molecular Cell Biology, Göttingen, Germany, and others |
Chapter 10 - Studies of Toxin Resistant Beta-Cells: Lessons for the Chemotherapy? Authors / Editors: Liu Hui-Kang, Division of Herbal Drugs and Natural Products, National Research Institute of Chinese Medicine, Taipei, Taiwan, ROC |
Chapter 10 - RENIN-ANGIOTENSIN SYSTEM AND DIABETES Authors / Editors: Kavaljit Chhabra, Kim Brint Pedersen and Eric Lazartigues Department of Pharmacology & Experimental Therapeutics and Cardiovascular Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, LA, 70112 |
Series: Cell Biology Research Progress |
Binding: Hardcover |
Pub. Date: 2011 1st quarter |
Pages: 6 x 9, 176 |
ISBN: 978-1-61761-212-1 |
Status: AV |
|
Status Code |
Description |
AN |
Announcing |
FM |
Formatting |
PP |
Page Proofs |
FP |
Final Production |
EP |
Editorial Production |
PR |
At Prepress |
AP |
At Press |
AV |
Available |
|
|
|
|