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01.D-Amino Acids: A New Frontier in Amino Acid and Protein Research - Practical Methods and Protocols
02.Cellular Signaling and Apoptosis Research
03.Cell Apoptosis Research Trends
04.Stem Cells and Cancer
05.Cell Growth Processes: New Research
06.Histological and Serological Tumor Markers and Gene Expression and Their Clinical Usefulness in Cancers
07.Foldases: Enzymes Catalyzing Protein Folding
08.Trends in Signal Transduction Research
09.Mast Cells: Roles, Interactions and Disorders
10.Stem Cell Research Developments
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Beta Cells: Functions, Pathology and Research
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Editors: Sarah E. Gallagher
Book Description:
Beta cells or β-cells, are a type of cell in the pancreas in areas called the islets of Langerhans. They make up 65-80% of the cells in the islets. Pancreatic B-cell is the only cell type that produces insulin to regulate glucose metabolism in the body. The insufficiency of insulin-producing B-cells results in dysregulation of blood glucose control, termed as type 1 diabetes. This book presents current research from across the globe in the study of Beta-cells, including the induction of pancreatic cancer cell death by elevated concentrations of extracellular zinc; the role of Rab GTPases and their effectors in the insulin secretory pathway of the pancreatic beta cell; In vivo reprogramming of pancreatic A-cells into B-like cells; and the role of glucocortoids, exercise and glucolipotoxicity with regard to stress and pancreatic B-cell function.
(Imprint: Nova Biomedical)

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Chapter 1 - Stress and Pancreatic β Cell Function: Role of Glucocortoids, Exercise and Glucolipotoxicity
Authors / Editors: Jacqueline Beaudry, Michael Riddell, York University, Kinesiology and Health Science, Toronto, Ontario, Canada

Chapter 2 - The Synergistic Effect of β Cell Replacement and Immunotherapy on the Treatment of Type 1 Diabetes
Authors / Editors: Dong-Sheng Li, Garth L.Warnock, Hong Lu, Long-Jun Dai, Hubei Key Laboratory of Embryonic Stem Cell Research, Tai-He Hospital, Yunyang Medical College, Shiyan, Hubei, China, and others

Chapter 3 - Antagonizing the Endocannabinoid Pathway Prevents the Development of Diabetes and β Cell Dysfunction in Zucker Diabetic Fatty Rats
Authors / Editors: V. Duvivier, Ch. Duquenne, V. Delion, F. Petoux, J. Ludop-Maignel, Ph. Chamiot-Clerc, M.P. Pruniaux, A.M. Galzin, Sanofi-Aventis R&D, Discovery Research Metabolism Department, Rueil-Malmaison, France
***Open Access Chapter. Free Download Available***

Chapter 4 - Diabetes Mellitus: An Opportunity for Therapy with Regenerative Medicine?
Authors / Editors: Akifumi Matsuyama, Department of Somatic Stem Cell Therapy and Health Policy, Foundation for Biomedical Research and Innovation, Kobe, Japan
***Open Access Chapter. Free Download Available***

Chapter 5 - Behind Beta Cell Glucotoxicity: A Pivotal Role of Glycoxidative Damage?
Authors / Editors: Alessandra Puddu, Daniela Storace, Department of Internal Medicine and Medical Specialties (Di.M.I.), University of Genova, Italy

Chapter 6 - Induction of Pancreatic Cancer Cell Death by Elevated Concentrations of Extracellular Zinc
Authors / Editors: Sundararajan Jayaraman, Arathi K. Jayaraman, University of Illinois at Chicago, Illinois

Chapter 7 - Rab GTPases Control Membrane Recycling in the Pancreatic Beta Cell
Authors / Editors: Toshihide Kimura, Ichiro Niki, Department of Pharmacology, Oita University Faculty of Medicine at Oita, Japan
***Open Access Chapter. Free Download Available***

Chapter 8 - In Vivo Reprogramming of Pancreatic -cells into β-like Cells
Authors / Editors: Ahmed Mansouri, Patrick Collombat, Max-Planck Institute for Biophysical Chemistry, Department of Molecular Cell Biology, Göttingen, Germany, and others

Chapter 10 - Studies of Toxin Resistant Beta-Cells: Lessons for the Chemotherapy?
Authors / Editors: Liu Hui-Kang, Division of Herbal Drugs and Natural Products, National Research Institute of Chinese Medicine, Taipei, Taiwan, ROC

Authors / Editors: Kavaljit Chhabra, Kim Brint Pedersen and Eric Lazartigues Department of Pharmacology & Experimental Therapeutics and Cardiovascular Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, LA, 70112

      Cell Biology Research Progress
   Binding: Hardcover
   Pub. Date: 2011 1st quarter
   Pages: 6 x 9, 176
   ISBN: 978-1-61761-212-1
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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