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Microglia: Biology, Functions and Roles in Disease
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Editors: Charanjit Kaur, Ling Eng-Ang (Yong Loo Lin School of Medicine, National University of Singapore)
Book Description:
The pioneering studies by several leading researchers in the early part of the last century first described the existence of microglial cells both in the early brain development and in pathological conditions. Microglial cells were later established to be the resident brain macrophages and immunocompetent cells present ubiquitously in the central nervous system including the retina in association with other glial cells, neurons and blood vessels. The book should be of interest to cell biologists and neuroscientists in general. Basic scientists, neuroimmunologists, neurologists, neuropathologists and neurosurgeons should find the latest information on microglial cells useful in their continued effort in searching and designing potential therapeutic strategies for treatment of neurological disease for which microglial cells are implicated. (Imprint: Nova Biomedical)

Please click on a chapter below to purchase separately

Chapter 1 - Microglia in the developing brain (pp. 1-28)
Authors / Editors: (Gurugirijha Rathnasamy, Eng-Ang Ling, Charanjit Kaur,Yong Loo School of Medicine, National University of Singapore)

Chapter 2 - The Mystic Embryonic Microglia: Its Origin, Function and Seeding (pp. 29-44)
Authors / Editors: (Yi Yin, Fei Li and Hua Feng, Southwest Hospital, Third Military Medical University, People's Republic of China)

Chapter 3 - Soldiers of the nervous system: Microglia in surveillance, offense and defense (pp. 45-71)
Authors / Editors: (Joseph M. Antony, Sunnybrook Research Institute, Toronto, Canada)

Chapter 4 - Microglia secretome: from neurotoxins to neurotrophins (pp. 73-91)
Authors / Editors: (Jocelyn M. Madeira, Jonathan P. Little, Andis Klegeris, Dept. of Biology, University of British Columbia Okanagan, Kelowna,BC, Canada)

Chapter 5 - The role of microglia in neurodegenerative disease; (pp. 93-117)
Authors / Editors: (Paul Su and Marios Politis, Hammersmith Hospital, Imperial College, London, UK)

Chapter 6 - Microglia function in Alzheimerís disease (pp. 119-131)
Authors / Editors: (Magdalena Sastre, Imperial College London, The Hammersmith Hospital, London, UK)

Chapter 7 - Blood Derived Microglia-Like Cells in Alzheimer's Disease (pp. 133-152)
Authors / Editors: (Jari Koistinaho, Johanna Magga, Tarja Malm,University of Eastern Finland, Kuopio)
***Open Access Chapter. Free Download Available***

Chapter 8 - Microglial functions against amyloid-‚ accumulation in brains of Alzheimerís disease (pp. 153-165)
Authors / Editors: (Kazuyuki Takata, Yoshihisa Kitamura, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto, Japan)

Chapter 9 - Modulation of microglial reaction in brain injury by novel therapeutic tools based on gene therapy approaches (pp. 167-182)
Authors / Editors: (Jean-Pierre Louboutin, David S. Strayer, Thomas Jefferson University, Philadelphia, PA, USA)

Chapter 10 - The application of inhibitors of microglial activation in brain diseases (pp. 183-196)
Authors / Editors: (Gang Xin, Kang-Sheng Li, Shantou University Medical College, Shantou, Guangdong, Chima)

Chapter 11 - Microglial activation is reduced by prostaglandin E2 (pp. 197-206)
Authors / Editors: (Takayuki Nagano, Shinya H. Kimura, and Motohiko Takemura, Hyogo College of Medicine, Japan)

Chapter 12 - Synaptic stripping and beyond: microglia or astrocytes? (pp. 207-217)
Authors / Editors: (Jun Yamada, Shozo Jinno, and Hiroshi Nakanishi, Graduate School of Medical Sciences, Japan and others )

Chapter 13 - Microglia-to-neuron communication in spinal nociceptive pathways (pp. 219-251)
Authors / Editors: (Francesco Ferrini, Chiara Salio, Adalberto Merighi, Dept. of Veterinary Morphophysiology, Grugliasco, Italy and others)

Chapter 14 - Microglia in Huntington disease (pp. 253-275)
Authors / Editors: (Colum Connolly, Austin Hill, and Blair R. Leavitt, The Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver,BC,Canada)

Chapter 15 - The neuroinflammatory role of Schwann cells in health and disease (pp. 277-303)
Authors / Editors: (Elke Ydens, Guillaume Lornet, Veerle Smits, Sofie Goethals, Vincent Timmerman, Sophie Janssens, University of Antwerp, Belgium and others)

      Cell Biology Research Progress
   Binding: Hardcover
   Pub. Date: 2012 2nd Quarter
   Pages: 7 x 10 (NBC - C) 321pp.
   ISBN: 978-1-61942-251-3
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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Microglia: Biology, Functions and Roles in Disease