Book Description:
Hyperthyroidism is the term for overactive tissue within the thyroid gland, resulting in overproduction and thus an excess of circulating free thyroid hormones. It is a common endocrine condition which most often is treated with thyrostatic drugs or radioiodine, less commonly with surgery. Graves' disease is the most common cause of primary hyperthyroidism and is characterized by goiter, palpitation and exophthalmos. This book discusses the pathogenesis, phenotypic expression and challenges in management for Graves' disease. The effectiveness of adrenergic blockers carvedilol, propranolol and verapamil on hyperthroidism associated insulin resistance is also examined. Furthermore, over the past two decades, there are increasing numbers of reports with a newly introduced group of unusual manifestations of hyperthyroidism. These unusual presentations make the diagnosis more challenging especially when they are the only presenting manifestations of the disease, or when the classical manifestations are subtle or overlooked.

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Table of Contents:
Preface

Differential Diagnosis of Hyperthyroidism pp.1-54 (Mehtap Cakir, Selcuk University, Meram School of Medicine, Division of Endocrinology and Metabolism, Konya, Turkey)

Atypical Variants of Graves’ Disease: Pathogenesis, Phenotypic Expression and Challenges in Management pp.55-90 (Rinkoo Jalan, Department of Endocrinology, Tan Tock Seng Hospital, Singapore)

Styles of Coping with Stress in Patients with Graves-Basedow Disease and Acceptance of the Illness pp.91-110 (Malgorzata Anna Basinska, Kazimierz Wielki University, Bydgoszcz, Poland)

Radioiodine Treatment of Hyperthyroidism pp.111-128
(Gertrud Berg, Ernst Nyström, Department of Oncology, Sahlgrenska University Hospital, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, and others)

Results of Orbital Decompression in Patients with Severe Thyroid Ophthalmopathy – Experience of 22 Years pp. 129-158(Radmilo Ronèeviæ, Clinical Center of Serbia, Clinic for Burns, Plastic and Reconstructive Surgery, Belgrade, Serbia)

Adjuvant Therapy in Hyperthyroidism pp.159-178 (Parloop A. Bhatt, Department of Pharmacology, L.M. College of Pharmacy, Gujarat, India)

Hyperthyroidism and Acute Thyroid Emergencies – A Discussion and Review of the Evidence Base pp.179-198 Helen Fenwick, Steven Gill, Jonathan Wilkinson, Speciality Registrar in Anaesthesia and Intensive Care Medicine, Nottingham University Hospitals, Nottingham, UK, and others)

Euthyroid Graves’ Disease: Pathogenesis and Treatment pp.199-218 (Kanji Sato, Division of Internal Medicine, Graduate School of Medicine,Tokyo Women’s Medical University, Tokyo, Japan)

Thyroid Receptor Antagonists: Possible Avenue in Management of Hyperthyroidism pp.219-238 (Parloop A. Bhatt, Department of Pharmacology, L.M. College of Pharmacy, Gujarat, India)

Efficacy of Carvedilol, Propranolol and Verapamil on Hyperthyroidism Associated Insulin Resistance – A Comparative Experimental Study pp.239-252
(Dharmesh Makwana, Parloop Bhatt, Department of Pharmacology, L.M.College of Pharmacy, Gujarat, India)

Thyroid Carcinoma and Hyperthyroidism pp.253-258 (N. Defne Altintas, Mustafa ªahin, Medicana International Ankara Hospital, Department of Internal Medicine, Ankara, Turkey, and others)

Autoimmune Thyroid Diseases and Cytotoxic T-Lymphocyte Associated Antigen 4 Gene pp.259-264 (N. Defne Altintas, Mustafa ªahin, Medicana International Ankara Hospital, Department of Internal Medicine, Ankara, Turkey, and others)

Unusual Presentations of Hyperthyroidism pp.265-270 (Mohamed Osama Hegazi, Mohamed Riyadh El-sonbaty, Medical Department, Al Adan Hospital, Kuwait)

Hyperthyroidism pp.271-294 (Rosa Maria Principe, Silvia Santos, Amelia Marí, Sonsoles Botella and Juan C Galofré, Department of Endocrinology, Clinica Universidad de Navarra, University of Navarra, Pamplona, Spain)

Hyperthyroidism: Etiology, Diagnosis and Treatment pp.295-314
(Wazir Muhammad, Department of Physics, Kyungpook National University, Daegu, South Korea)

Managing Moderate to Severe Graves Ophthalmopathy: An up-to-date Review pp.315-332
(Christopher I. Zoumalan, Kimberly P. Cockerham, Michael Kazim - Divison of Ophthalmic Plastic and Reconstructive Surgery, Department of Ophthalmology, New York University, Langone School of Medicine, New York, NY, Department of Ophthalmology, Stanford University School of Medicine, Stanford, CA, USA, and others)

Thyroid Function in Infants with Mothers with Graves' Disease and Hyperthyroidism During Pregnancy pp.333-344
(Ryuzo Higuchi and Sawako Minami - Department of Perinatal Medicine, Divisions of NICU, and others)

Immuno-pathogenesis of Thyroid Associated Ophthalmopathy (TAO): The Effect of Novel Treatment of TAO with anit-TNF and anit- CD 20 Monoclonal Antibodies pp.345-358
(Jan Komorowski and Henryk Stêpieñ - Department of Clinical Endocrinology and Department of Immunoendorinology, The Medical University of £ódŸ, Poland)

Index pp.359-384