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Better Understanding of the Campylobacter Conundrum
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Authors: Amélie Garénaux (Sécurité des Aliments, Ecole Nationale Vétérinaire de Nantes Route de Gachet, France), Céline Luchetti-Miganeh and Gwennola Ermel (Interactions Cellulaires et Moléculaires, Université Rennes 1, France), et al. 
Book Description:
Campylobacter jejuni is a microaerophilic and thermophilic pathogen genetically close to Helicobacter pylori. It represents one of the most of concern emerging food pathogens, as it is one of the primary sources of human enteritis, in developed as well as in developing countries. It is also a source of rare but serious neuropathies. Interest in this bacterium has constantly been growing during the last decade, since many antibiotic resistant strains are emerging. The sequencing of C. jejuni genome has revealed a small genome in which a lot of regulation systems are fully understood in well-studied bacteria were absent. To infect humans, a pathogen has to survive different environmental stresses and attacks of the immune system, and also be able to express its virulence factors. The Campylobacter conundrum is the latter: how does this microaerophilic (=sensitive to oxygen) bacterium, owning a small genome and lacking most of the well-known regulation systems, still constitute a hazard for humans? From what is known about C. jejuni genome, this book proposes to draw a parallel between on the one hand the different mechanisms and regulation pathways existing, and on the other hand stress resistance and virulence of this emerging food pathogen.


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Table of Contents:
Preface

Introduction
1. General Introduction

2. Campylobacter Jejuni and Food Safety

3. Campylobacter Genomes: General and Specific Features
(Frederique Barloy Hubler)

4. From Environment to the Host: Stress Resistance Mechanisms and Regulation Pathways

5. Other Strategies Developed by Campylobacter to Adapt to the Environment

References

Index

   Binding: Softcover
   Pub. Date: 2008, 3rd Quarter
   ISBN: 978-1-60456-636-9
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Better Understanding of the Campylobacter Conundrum