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01.Kynurenines in the Brain: From Experiments to Clinics
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Kynurenines in the Brain: From Experiments to Clinics
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Editors: Laszlo Vecsei (University of Szeged)
Book Description:
This book focuses on the metabolism, analytical chemistry and role of kynurenine metabolites in different disorders of the central nervous system. Furthermore, neurodegenerative models and pharmacological investigations with kynurenine metabolites and possible therapeutic perspectives are discussed.

Table of Contents:
Preface

I. Metabolism, analytical chemisty and possible role of kynurenine metabolites in disorders of the central nervous system;

Chapter 1. Analytical chemistry of kynurenine and its metabolites;
pp. 3-32
(Arvidsson, B., Bergquist, J.)


Chapter 2. The possible role of excitotoxins and kynurenine aminotransferase in neurodevelopmental processes; pp. 35-49
(Csillik, A, Okuno, E., Knyihár-Csillik, E., Vécsei, L.)


Chapter 3. Inflammation and the oxidative metabolism of tryptophan in the mammalian brain; pp. 51-69
(Forrest, C. M., Mackay, G. M., Stoy, N., Darlington, L. G., Stone, T. W.)


Chapter 4. Kynurenine metabolites in neurological and psychiatric disorders; pp. 71-80
(Klivényi, P., Vécsei, L.)


II. Neurodegenerative models and pharmacological investigations with kynurenine metabolites

Chapter 5. Experimental models of neurodegenerative disorders: Effects of mitochondrial toxins on kynurenine aminotransferase immunoreactivity; pp. 83-115
(Knyihár-Csillik, E., Csillik, A. E., Krisztin-Péva, B., Dobó, E., Vécsei, L.)


Chapter 6. Mitochondrial toxins with potent neurodegenerative and convulsive properties – effects on kynurenine metabolism in the brain; pp. 117-133
(Urbanska, E. M.)


Chapter 7. Electrophysiological and behavioral studies with kynurenine and related compounds; pp. 135-161
(Németh, H., Toldi, J., Vécsei, L.)


Chapter 8. Regulation of corticocerebral blood flow: the possible role of kynurenine system; pp. 163-172
(Sztriha, L. Sas, K., Vécsei, L.)


III. Therapeutic perspectives

Chapter 9. Neuroprotection and kynurenine system; pp. 173-191
(Kiss, Cs., Vécsei, L.)


Index

   Binding: Hardcover
   Pub. Date: 2005
   ISBN: 1-59454-365-8
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Kynurenines in the Brain: From Experiments to Clinics