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Characteristics of Coronary Artery Disease in Women: An Experience at Moroccan Hospital (pp.271-276) $100.00
Authors:  (E. Zbir, N. Mouine, M. Raissouni, A. Bouzerda, M. Sabry, T. El Hankari, A. Chaib, A. Benyass, A. Moustaghfir, A. Boukili, M. Nazzi, A. Hamani, Department of Cardiology, Mohammed V Instruction Military Hospital, Rabat, Morocco)
Abstract:
Introduction: The incidence of coronary artery disease is increasing due to lifestyle changes and the large number of risk factors including diabetes. The goal of this chapter is to study the particularities of coronary artery disease in Moroccan woman. Materials and Methods: The authors report a retrospective study concerning 58 women (group 1) hospitalized for coronary artery disease between January 2009 and December 2010 compared to a sample of 138 men (group 2) hospitalized for coronary artery disease too, during the same period. Results: The average age of women was 60.19 9.5 years and 59.6 8.6 years for men. Smoking is frequent in men (75.3% versus 3.4%), hypertension, diabetes and metabolic syndrome are more common in women (respectively 65.5%, 62%, 34, 5% versus 42%, 43.5%, 12.3%). Clinically, the mode of presentation of coronary artery disease in women is the stable angina of effort and / or atypical chest pain (50%), acute coronary syndromes represent 32.7% (group 1) and 60.8% (group 2). Echocardiography showed wall motion abnormalities in 24.1% in group 1 and left ventricular systolic dysfunction in 12% versus 55% and 35.5% respectively in group 2. Angiographically, the single-vessel disease is common in women (36.2% versus 12.3%), normal coronary lesions or insignificant are found in 20.6% of group 1 versus 4.3% in group 2.Three vessel disease and distribution of coronary lesions are frequent in man (46.3% versus18, 9%). All of our patients have received conventional medical treatment with correction of cardiovascular risk factors. Coronary angioplasty with stenting is widely practiced in group 1 (37.9% versus 10.1%). On a mean follow up of 3 months (1 and 24 months), we deplored two deaths in each group. The thrust of left heart failure were respectively 5.1%, 6.8% (group 1) versus 31.8%, 42% (group 2). Conclusion: Coronary artery disease in women is less common, and occurs with a lot of
cardiovascular risk factors, integrating the metabolic syndrome. The clinical picture is very often a stable angina, a few diffused coronary lesions but prognosis is usually good. 


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Characteristics of Coronary Artery Disease in Women: An Experience at Moroccan Hospital (pp.271-276)