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10.Therapeutic Perspectives of Gastrointestinal Melatonin (pp. 233-252)
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Diagnostic Modalities in Crohn's Disease
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Authors: Carlo M. Girelli (Chief of the IBD Unit, Gastroenterology and Digestive Endoscopy Service. 1st Division of Internal Medicine. Hospital of Busto Arsizio (VA), Italy a) Luca G. Crespi (Division of Radiology, Hospital of Busto Arizio (VA) Italy) 
Book Description:
Inflammatory bowel disease is a heterogeneous group of chronic, idiopathic, immune-mediated, inflammatory disorders of the gastrointestinal tract, including Crohn’s disease and ulcerative colitis. In this book, the reader will find a preliminary section on the etiopathogenesis, epidemiology, and clinical-pathologic aspects of Crohn’s disease, and - bearing in mind that the best therapeutic choice begins with an accurate diagnosis - an attempt to provide an updated, comprehensive view of the state-of-the-art endoscopic and radiologic procedures used in the diagnosis, staging and management of Crohn’s disease with special emphasis on test appropriateness in the various clinical setting.

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Table of Contents:

Forewords: CM Girelli, LG Crespi

Section 1: Crohn’s disease

Chapter 1, Etiopathogenesis pp. 3-20
CM Girelli
• Introduction
• Genetics
• The luminal environment and the intestinal epithelial barrier
• The immune response
• Cell trafficking
• The infectious theory
• Environmental factors

Chapter 2, Epidemiology pp. 21-33
CM Girelli
• Introduction
• Incidence
• Prevalence
• Mortality
• Sex and age distribution
• Ethnicity
• Risk factors
• The “Hygiene Hypothesis”
Chapter 3, Pathology and Clinical Features pp. 35-50
CM Girelli
• Pathology
• Clinical picture
• Laboratory markers
• Complications
• Activity and severity assessment
• Classification of Crohn’s disease
• Clinical course
• Differential diagnosis

Section 2: Endoscopic Diagnosis

Chapter 4, Ileocolonoscopy 53-68
CM Girelli
• Introduction
• Clinical indication
• Safety
• Bowel cleansing
• Reasons for incomplete examinations
• Lesional pattern in Crohn’s disease
• Endoscopic differential diagnosis
• Endoscopic assessment of disease extent and severity
• Endoscopic assessment of disease recurrence
• Endoscopic detection and management of complications

Chapter 5, Enteroscopy pp. 69-91
CM Girelli
• Introduction
• Capsule Endoscopy
• Double Balloon Enteroscopy
• Single Balloon Enteroscopy

Section 3: Radiologic Diagnosis

Chapter 6, Contrastographic Radiological Imaging pp. 95-105
FF Francone, LG Crespi , S Zaid
• Introduction
• Technique
• Radiographic findings
• Conclusion
Chapter 7, Computed Tomography Imaging 107-122
LG Crespi, FF Francone, S Zaid
• Introduction
• Technique
• CT Features
Chapter 8, Magnetic Resonance Imaging pp. 123-132
S Zaid, FF Francone, LG Crespi
• Introduction
• Cross-sectional imaging
• Technique
• Signs and disease activity correlation
• Conclusion
Chapter 9, Intestinal Ultrasound pp. 133-145
CM Girelli
• Introduction
• Pathological and ultrasonographic correlations
• Limitations and collocation in the diagnostic of Crohn’s disease


   Binding: Hardcover
   Pub. Date: 2009
   Pages: 164 pp.
   ISBN: 978-1-60692-701-4
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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Diagnostic Modalities in Crohn's Disease