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Handbook on Mass Spectrometry: Instrumentation, Data and Analysis, and Applications
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Editors: J. K. Lang
Book Description:
Mass spectrometry (MS) is an analytical technique for the determination of the elemental composition of a sample or molecule. It is also used for elucidating the chemical structures of molecules, such as peptides and other chemical compounds. MS instruments consist of three modules: an ion source, which splits the sample molecules into ions; a mass analyzer, which sorts the ions by their masses by applying electromagnetic fields; and a detector, which measures the value of an indicator quantity and thus provides data for calculating the abundances of each ion present. The technique has both qualitative and quantitative uses. These include identifying unknown compounds, determining the isotopic composition of elements in a molecule, and determining the structure of a compound by observing its fragmentation. Other uses include quantifying the amount of a compound in a sample or studying the fundamentals of gas phase ion chemistry. MS is now in very common use in analytical laboratories that study physical, chemical, or biological properties of a great variety of compounds. This new book gathers the latest research from around the globe in the field.

Table of Contents:

Chapter 1. Mass Spectrometric Characterization of Organometallic Compounds, pp.1-38
(Robert Jirásko and Michal Holčapek, Department of Analytical Chemistry, Faculty of Chemical Technology, University of Pardubice, Czech Republic)

Chapter 2. LC-MS Based Metabolomics, pp.39-74
(Ruben t’Kindt and Jan Van Bocxlaer, Laboratory of Medical Biochemistry and Clinical Analysis, Ghent University, Ghent, Belgium)

Chapter 3. Biomarker Discovery for Cancer Diagnosis Using Serum Proteomic Analysis: From Basic Research to Clinical Application, pp.75-112
(Yo-ichi Ishida, Hirofumi Uto, Akihiko Okayama , and Hirohito Tsubouchi, Miyazaki Prefectural Industrial Support Foundation, Miyazaki, Japan, and others)

Chapter 4. Quantitative LC-MS Analysis of Proteins using Trypsin and CNBr Generated Marker-Peptides: A Proof-of-Concept Study on Cystatin C, pp.113-142
(Michael L. Storme and Jan F. Van Bocxlaer, Laboratory of Medical Biochemistry and Clinical Analysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium)

Chapter 5. High Irradiance Laser Ionization Mass Spectrometry for Direct Elemental Analysis of Solids, pp.143-172
(Wei Hang, Lizhi Chen, Quan Yu, Rongfu Huang, Lingfeng Li, Yiming Lin, Jian He, Benli Huang, Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, China)

Chapter 6. Quantification of Endocannabinoids in Clinical Samples: Pitfalls and Future Directions, pp.173-200
(H.Timothy, Marczylo and Justin.C.Konje, Endocannabinoid Research Group, Reproductive Sciences Section, Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester, UK)

Chapter 7. Study of Oxide-Based Interferences on Trace Elements Determination in ICP-MS, pp.201-224
(Sonia D’Ilio, Francesco Petrucci, Oreste Senofonte, Nicola Violante, Department of Environment and Primary Prevention, Istituto Superiore di Sanità, Rome, Italy)

Chapter 8. Biomarkers of Lipid Peroxidation: Quantification of Isoprostanes and other Oxidation Products by Mass Spectrometry, pp.225-246
(Emilie Mas, Jean Paul Cristol, Françoise Michel, Service de Biochimie, Hôpital Lapeyronie, Montpellier, France, and others)

Chapter 9. Mass Spectrometry Evaluation of the Improvement of DLC Film Lifetime Using Silver Nanoparticles for Application on Space Devices: Material Review and Etching Experiments, pp.247-268
(F.R. Marciano, L.F. Bonetti, R.S. Pessoa, J.S. Marcuzzo, M. Massi, L.V. Santos, E.J. Corat and V.J. Trava-Airoldi, National Institute of Space Research (INPE), Sao Jose dos Campos, Brazil, and others)

Chapter 10. Application of Electrospray Ionization-Mass Spectrometry to the Discrimination of Green and Roasted Coffees by Species and Quality, pp.269-290
(Juliana C.F. Mendonça, Adriana S. Franca, Leandro S. Oliveira, Robson J.C.F. Afonso, Programa de Pós-Graduação em Ciência de Alimentos, Universidade Federal de Minas Gerais, Brasil, and others)

Chapter 11. Recent Developments on GC/MS Analysis of Aroma Compounds of Baked Cereal Products, pp.291-306
(Adamantini Paraskevopoulou, Laboratory of Food Chemistry and Technology, School of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, Greece)

Chapter 12. Derivatization GC-MS techniques on plastic food contact materials, pp.307-324
(Jun Hyun Sung, Hyun Jin Park, Graduate School of Biotechnology, Korea University, Seoul 136-701, Korea, and others)^

Chapter 13. Optical Control of Ion Sputtering, pp.325-344
(A.G. Rokakh, A.A .Serdobintsev, S.V. Stetsyura, A.G. Zhukov, M.D. Matasov, I.V. Malyar, Saratov State University, Russia)

Chapter 14. A Review of Applications of GC-MS in Combination with SPME for Flavour Analysis of Cheeses, p.345-370
(Verzera, C. Condurso, Dipartimento di Chimica Organica e Biologica, University of Messina, Messina, Italy)p

Chapter 15. Advanced Techniques and Recent Applications of Mass Spectrometry in Foods and Beverages, pp.371-388
(Andréa Pittelli, Boiago Gollücke and Rodrigo Ramos Catharino, Nutrition Department., Catholic University of Santos, Nébias, Brazil)

Chapter 16. A New Method for N- and C-terminal de novo amino acid Sequencing of Proteins by Mass Spectrometry, pp.389-420
(Hiroki Kuyama, Osamu Nishimura, and Susumu Tsunasawa, Institute for Protein Research, Osaka University, Suita, Japan)

Chapter 17. Comparative Proteomic Analysis Reveals Neuroprotective Effects of Peony Root Extract on Cobalt-Induced Seizure in Mice, pp.421-434
(Kagemasa Kajiwara, Minoru Kimura, Division of Basic Molecular Science and Molecular Medicine, Kanagawa, Japan and others)

Chapter 18. Application of Electronic Noses in the Wine Industry, pp.435-446
(Daniel Cozzolino, Wies Cynkar and Robert Dambergs, the Australian Wine Research Institute, Glen Osmond, Australia)

Chapter 19. Pyrolysis Gas Chromatography-Mass Spectrometry Study of Weathered Wood Plastic Composites, pp.447-458
(James S. Fabiyi and Armando G. McDonald, Department of Forest Products, University of Idaho, Moscow, ID)

Chapter 20. Proton-Affinitive Derivatization in LC-ESI-MS/MS Analyses of Hydroxysteroids, pp.459-464
(Kouwa Yamashita and Mitsuteru Numazawa, Faculty of Pharmaceutical Sciences, Tohoku Pharmaceutical University, Miyagi, Japan)

Chapter 21. Applications of Mass Spectrometry in the Analysis of Coffee Components ^, pp.465-498
(Daniel Perrone and Adriana Farah, Laboratório de Bioquímica Nutricional e de Alimentos, Departamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Brazil)

Index pp.499-525

      Chemistry Research and Applications
   Binding: Hardcover
   Pub. Date: 2009
   Pages: 525.pp
   ISBN: 978-1-60741-580-0
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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Handbook on Mass Spectrometry: Instrumentation, Data and Analysis, and Applications