Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
            
  Top » Catalog » Books » My Account  |  Cart Contents  |  Checkout   
Quick Find
  
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
_Cancer Research Journal - This journal ceased publication after 4#4 (2010). Back Issues are available.
$195.00
Shopping Cart more
0 items
Information
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Notifications more
NotificationsNotify me of updates to Research Progress In Alzheimer's Disease and Dementia. Volume 4
Tell A Friend
 
Tell someone you know about this product.
Research Progress In Alzheimer's Disease and Dementia. Volume 4
Retail Price: $280.00
10% Online Discount
You Pay:

$252.00
Editors: Miao-Kun Sun (Blanchette Rockefeller Neurosciences Inst., 9601 Medical Center Dr., Rockville, MD)
Book Description:
Alzheimer¡¯s disease (AD), the most common form of neurodegenerative disorder in the elderly, is characterized pathologically by extracellular amyloid plaques and intracellular neurofibrillary tangles, pathophysiologically by synaptic dysfunction, and clinically by a progressive decline in cognition. Currently, AD has no cure and its prevalence is predicted to triple by 2050 with the rapid increase in the aging population, unless more effective prevention/treatments are developed. Since the publication of the third book volume, the rapid progress in the research fields of AD and dementia continues through the intensive efforts of research scientists worldwide. This fourth book volume contains 12 chapters, bringing together a presentation of scientific frontiers in current AD/dementia research. The topics include emotional memory in AD, amyloid-B clearance, synaptic transmission-mediated regulation of amyloid-B dynamics, anti-AD immunotherapy, clinical trials of AD therapeutics using AD transgenic mouse models, roles of apolipoprotein E, chronic inflammation, cathepsins, and gelsolin in AD pathogenesis and as anti-AD therapeutic targets/agents, declarative memory impairment and hippocampal atrophy in Parkinson¡¯s disease, fronto-temporal dementia, and cognitive impairment in schizophrenia. These chapters cover current advances in our understanding of the pathogenic mechanisms underlying AD and dementia, in the diagnosis of early AD and dementia, and in the development of therapeutic agents that target memory-relevant AD pathogenesis. The book will be highly valuable to students and scientists worldwide who are interested in the scientific research progress in AD and memory disorders.

Table of Contents:
Preface

1. Emotional Memory in Alzheimer¡¯s Disease
(Jill D. Waring and Elizabeth A. Kensinger, Department of Psychology, Boston College, Chestnut Hill, MA USA) pp.9-36

2. Mechanisms of Amyloid-B Clearance in Alzeheimer's Disease
(Joseph El Khoury, Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy, and Immunology and Division of Infectious Diseases, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, and Suzanne E. Hickman, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA)pp.37-66

3. Synaptic transmission regulates amyloid-¦Â dynamics
(John R. Cirrito, Department of Neurology, Washington University School of Medicine, St. Louis, MO)pp.67-84

4. Anti-AB Antibodies For the Treatment of Alzheimer's Disease
(Bin Liu*, Hongjun Fu*, Jeffrey L. Frost, and Cynthia A. Lemere Center for Neurologic Disease, Brigham & Women¡¯s Hospital and Harvard Medical School, Boston, MA)pp.85-112

5. The Failure of the APP Transgenic Mouse Models to Predict Efficacy of Agents in Five Clinical Trials of Alzheimer¡¯s Disease Suggests That There is a Need for a New Paradigm for Drug Development.
(Jordan L. Holtzman, University of Minnesota, Minneapolis, MN)pp.113-144

6. Apolipoprotein E and Alzheimer¡¯s Disease: An Update on Allele-Specific Effects of Disease Etiology
(Ann M. Saunders, Genetics Research GlaxoSmithKline R&D
Research Triangle Park, NC)pp.145-160

7. Chronic Inflammation and Alzheimer¡¯s Disease
(Douglas G. Walker, Jason Yuan and Lih-Fen Lue, Sun Health Research Institute, Sun City, AZ)pp.161-184

8. Cathepsins in Alzheimer¡¯s disease and dementia: Cathepsin inhibitors as potential anti-dementic therapeutics
(Azizul Haque, Naren L. Banik1,and Swapan K. Ray, Medical University of South Carolina, Charleston, SC and University of South Carolina School of Medicine, Columbia, SC)pp.185-198

9. Role of gelsolin in Alzheimer¡¯s disease
(Lina Ji, Abha Chauhan, Ved Chauhan, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY)pp.199-218

10. Declarative memory impairment and hippocampal atrophy in Parkinson¡¯s disease
(Carme Junque, Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Spain)pp.219-242

11. Fronto-temporal dementia
(Alfredo Postiglione, Graziella Milan and Sabina Pappat¨¤, University of Naples, Naples, Italy and Institute of Biostructures & Bioimaging, CNR, Naples, Italy)pp.243-262

12. Cognitive impairment in schizophrenia
(Verity C Leeson and Eileen M Joyce, UCL Institute of Neurology, Queen Square, London) pp.263-280

Index pp.281-306

   Series:
      Research Progress in Alzheimer's Disease and Dementia
   Binding: Hardcover
   Pub. Date: 2011 - 1st Quarter
   Pages: 306.pp
   ISBN: 978-1-60876-152-4
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
Special Focus Titles
01.Violent Communication and Bullying in Early Childhood Education
02.Cultural Considerations in Intervention with Women and Children Exposed to Intimate Partner Violence
03.Chronic Disease and Disability: The Pediatric Lung
04.Fruit and Vegetable Consumption and Health: New Research
05.Fire and the Sword: Understanding the Impact and Challenge of Organized Islamism. Volume 2

Nova Science Publishers
© Copyright 2004 - 2020

Research Progress In Alzheimer's Disease and Dementia. Volume 4