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Human Spermatozoa: Maturation, Capacitation and Abnormalities
Retail Price: $395.00
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$355.50
Editors: Thomas Lejeune and Pascal Delvaux
Book Description:
Spermatozoa is the basic human male germ cell. This gametocyte plays an important role in fertilization. In the past five years, new improvements in diagnosis have allowed us to assess male fertility potential with a new perspective studying with demonstrated role in sperm physiology. Furthermore, it is demonstrated that infertile men have high levels of sperm DNA damages and a small percentage of spermatozoa from fertile men also possess detectable levels of DNA damage. This book examines several of the factors that may be involved in sperm chromatin and DNA anomalies, including intra and extra testicular factors. Furthermore, sperm capacitation is a complex physiological process that involves biochemical, biophysical, molecular and metabolic modifications of all sperm domains. Some important events related to the capacitation process of sperm is examined as well. The biological role of the proteasome during sperm capacitation and the acrosome reaction and its relationship with protein phosphorylation and dephosphorylation during these processes is explored as well. Other chapters in this book highlight the pivotal role of transmission electron microscopy (TEM) analysis in the diagnosis of human sperm pathologies, the barrier methods currently available to men for regulating their fertility, a discussion of the current understanding of gene transfer to the testis, a new perspectives for the study of mycoplasmal and chlamydial infections of human spermatozoa and a discussion of the present current knowledge on the mechanisms, molecules and cell signaling involved in sperm activating ability.

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Chapter 1 - Sperm Nuclear Maturation: A Basic and Clinical Approach pp.1-86
Authors / Editors: (Talebi, Ali Reza (A. R.), Department of Biology and Anatomical Sciences, Research & Clinical Center for Infertility, Shahid Sadoughi Medical University, Yazd, Iran)

Chapter 2 - Sperm Capacitation: Physiology, Molecular Mechanisms and Relevance for Fertilization pp.87-122
Authors / Editors: (Rita de Cássia da Silveira e Sá, Reproduction Biology Center/Biology Department, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil)

Chapter 3 - Role of the Human Sperm Proteasome during Capacitation and the Acrosome Reaction: Interaction with Protein Kinases and Phosphatases pp.123-154
Authors / Editors: (Janetti Signorelli, Emilce S. Diaz, Patricio Morales, Department of Biomedicine, Faculty of Health Sciences, University of Antofagasta, Antofagasta, Chile)

Chapter 4 - Development and Maturation of Human Germ Cells and Disorders of Those Processes in Childhood pp.155-182
Authors / Editors: (Zivkovic Dragana, Hadziselimovic Faruk, Institute for Child and Youth Health Care of Vojvodina, Novi Sad, Serbia, and others

Chapter 5 - Family Planning, Male Contraception, and Reproductive Health pp.183-204
Authors / Editors: (Daulat R.P. Tulsiani, Departments of Obstetrics & Gynecology, and Cell & Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA)

Chapter 6 - Effects of the Seminal Plasma Proteins Semenogelin (SEMG)/Seminal Vesicle Secretion 2 (SVS2) on Sperm Fertility pp.205-220
Authors / Editors: (Kaoru Yoshida, Teruaki Iwamoto, and Manabu Yoshida, Biomedical Engineering Center, Toin University of Yokohama, Yokohama 225-8502, Japan)

Chapter 7 - Gene Therapy for Male Infertility: Potential and Limitation pp.221-242
Authors / Editors: (Yoshiyuki Kojima, Kentaro Mizuno, Shoichi Sasaki, Yutaro Hayashi, Kenjiro Kohri, Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan)

Chapter 8 - Capacitation and Acrosome Reaction pp.243-262
Authors / Editors: (Fábio F. Pasqualotto, Luana Venturin Lara, Eleonora Bedin Pasqualotto, Instituto de Biotecnologia e Centro de Ciências da Saúde, Universidade de Caxias do Sul, RS and CONCEPTION – Centro de Reprodução Humana, Caxias do Sul, RS, Brasil)

Chapter 9 - Impaired Function of the Spermatozoa: Links with Mycoplasmal and Chlamydial Infections pp.263-286
Authors / Editors: (Díaz-García Francisco Javier, Flores-Medina Saul, Giono-Cerezo Silvia, Departamento de Salud Pública, Facultad de Medicina, Universidad Nacional Autónoma de México, México, and others)
***Open Access Chapter. Free Download Available***

Chapter 10 - Clinic Management of Men with Macrocephalic Sperm Head Syndrome pp.287-306
Authors / Editors: (Kahraman Semra, Candan ZN, Memorial Hospital ART & Reproductive Genetics Centre, Istanbul, Turkey)

Chapter 11 - Mitochondria and Spermatozoa pp.307-326
Authors / Editors: (Pascale May-Panloup, Yves Malthiery, Pascal Reynier, Département de Pathologie Cellulaire et Tissulaire, Centre Hospitalier Universitaire, Angers, France, and others)

Chapter 12 - Recent Insights into Spermatozoa Development and Ultrastructure in the Eucestoda pp.327-354
Authors / Editors: (Magdaléna Bruňanská, Parasitological Institute, Slovak Academy of Sciences, Košice, Slovak Republic)

Chapter 13 - The Use of Pentoxifylline for Triggering the Movement of Testicular Sperm before their Use in Intracytoplasmic Sperm Injection in Men with Azoospermia pp.355-378
Authors / Editors: (Borut Kovacic, Veljko Vlaisavljevic, Department of Reproductive Medicine and Gynecologic Endocrinology, University Clinical Centre Maribor, Slovenia)

Chapter 14 - Sperm Induced Oocyte Activation pp.379-398
Authors / Editors: (Elisabetta Tosti, Yves Ménézo, Laboratory of Animal Physiology and Evolution, Stazione Zoologica, Naples, Italy, and others)

Chapter 15 - DNA Integrity and mRNA Expression Profile as Indicators of Sperm Quality and Assisted Reproduction Outcome pp.399-418
Authors / Editors: (Marcos Meseguer, Sandra García-Herrero, Thamara Viloria, Rebeca Santiso, Jose Luis Fernández, Nicolás Garrido, Instituto Valenciano de Infertilidad,,Universidad de Valencia, Valencia, Spain, and others

Chapter 16 - Concern about the Possibility of Seminal Quality Decline in World Men Population pp.419-432
Authors / Editors: Andrea Giannot(Andrea Giannotti Galuppo, Roseli Fernandes Gonçalves, Embryology and Animal Reproduction Biotech Laboratory, College of Veterinary Medicine, Rio Grande do Sul Federal University, RS, Brazil, and others)

Chapter 17 - Sperm in Seropositive Males for HIV or HCV pp.433-448
Authors / Editors: (Nicolás Garrido, José Remohí, José Bellver, Marco A. Melo-Barreto, Antonio Pellicer, Marcos Meseguer, Instituto Universitario IVI, Universidad de Valencia, Valencia, Spain, and others)

Chapter 18 - The Heterochromatic Component of the Human Y Chromosome: A Genetic Wasteland or Something More? Suggestions from the Fruitfly pp.449-462
Authors / Editors: (Roberto Piergentili, Sapienza – Università di Roma, Department of Genetics and Molecular Biology, Rome; Italy)

Chapter 19 - Maintenance of the Cryopreserved Sperm in the Fertility Clinic is a Risky Task: Precautionary Note for the Clinics pp.463-472
Authors / Editors: (Amjad Hossain, John Phelps, Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas, USA)

Chapter 20 - Integrins in Human Spermatozoa: Their Role in Fertilization Process pp.473-482
Authors / Editors: (Roseli Fernandes Gonçalves, Andrea Giannotti Galuppo, Valquiria Hyppolito Barnabe, Department of Animal Reproduction, College of Veterinary Medicine and Animal Sciences, São Paulo University, São Paulo, SP, Brazil, and others)

Chapter 21 - Heavy Metal Contaminants and Male Reproductive Health pp.483-490
Authors / Editors: (Debjani Nath, Department of Zoology, University of Kalyani, West Bengal, India)

Chapter 22 - Interactions between Visible Light and Sperm Cells pp.491-500
Authors / Editors: (Rachel Lubart, Departments of Chemistry and Physics, Bar-Ilan University, Ramat-Gan, Israel)

Chapter 23 - Energy Consumption in Semen due to the Protein Glycosylation in Poorly Controlled Diabetes Mellitus pp.501-506
Authors / Editors: (Viroj Wiwanitkit, Wiwanitkit House, Bangkhae, Bangkok, Thailand)

Chapter 24 - Spermatozoa in Zero Gravity Space: A New Concern pp.507-510
Authors / Editors: (Viroj Wiwanitkit, Wiwanitkit House, Bangkhae, Bangkok, Thailand)

Chapter 25 - Estrogen Usage in Gay: Effect on Spermatozoa? pp.511-514
Authors / Editors: (Viroj Wiwanitkit, Wiwanitkit House, Bangkhae, Bankgok Thailand)

   Series:
      Human Reproductive System - Anatomy, Roles and Disorders
   Binding: Hardcover
   Pub. Date: 2012
   Pages: pp.545
   ISBN: 978-1-60876-401-3
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Human Spermatozoa: Maturation, Capacitation and Abnormalities