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Handbook of Free Radicals: Formation, Types and Effects |
Retail Price: |
$395.00 |
10% Online Discount You Pay: |
$355.50 |
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Editors: Dimitri Kozyrev and Vasily Slutsky |
Book Description: Free radicals are molecules, ions, or atoms with unpaired electrons in their outermost shell of electrons. Although it is a relatively recent discovery, the occurrence of free radicals in biological processes is now widely accepted. Free radicals are involved in the pathogenesis of many diseases, such as diabetes, cardiovascular and pulmonary diseases and also in inflammation. Free radicals are also involved in important physiological processes, such as ageing. Free radicals are constantly formed in the human body, but they can become toxic when generated in excess or in the presence of a deficiency in the naturally occurring antioxidant defences. In general, the body has adequate antioxidant defences to cope with the production of free radicals under physiological conditions. This book reviews the updated knowledge on free radicals and its possible mechanisms in neurological disorders and in some oxidative stress processes, such as in intractable epilepsy and febrile seizures. Some approaches useful to elucidate the effects of free radical exposure on the overall protein structure are also discussed. Additionally, the potential risk factors and major cellular events contributing to the generation of reactive oxygen species and retinal pigment epithelium (EPI)/photoreceptor cell damage, and their roles in the pathogenesis of AMD are examined. Furthermore, thyroid cells are a unique model to study free radical processes involving reactive oxygen and iodine species. The role of oxidative stress in impairment in the thyroid function is explored. Other chapters in this book explore free radicals and its role in the in vivo disease control of malaria, as well as the monitoring of free radical in ultrasonic field in vitro and in vivo, its role in laboratory medicine, the relationship between rabies and free radicals, the correlation between exercise and free radical production, and the role of free radicals in several homeostatic processes through methods that can be used to detect free radicals either directly or indirectly (also known as fingerprinting methods).
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Chapter 1 - OXIDATIVE STRESS IN CANCER AND NEURODEGENERATIVE DISEASES: PREVENTION AND TREATMENT BY DIETARY ANTIOXIDANTS, pp. 1-55 Authors / Editors: (Anupam Bishayee and Altaf Darvesh, Departments of Pharmaceutical Sciences and Psychiatry, Northeastern Ohio Universities Colleges of Medicine and Pharmacy) |
Chapter 2 - THERAPEUTIC POTENTIAL OF FREE RADICAL SCAVENGERS IN NEUROLOGICAL DISORDERS, pp. 57-97 Authors / Editors: (Faizul Azam, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Seventh of October University, Misurata, Libya) |
Chapter 3 - MITOCHONDRIAL REACTIVE OXYGEN SPECIES AND CANCER, pp. 99-116 Authors / Editors: (Gabriel D. Dakubo, Genesis Genomics Inc., Ontario, Canada) |
Chapter 4 - FREE RADICAL PRODUCTION DURING EXERCISE: SOURCES AND EFFECTS, pp. 117-152 Authors / Editors: (Pedro Tauler, Antoni Aguiló, Departament de Biologia Fonamental i Ciències de la Salut, Universitat de les Illes Balears, Palma de Mallorca, Spain, and others) |
Chapter 5 - THE BRAIN REDOX PARADOX OF PHYSICAL EXERCISE, pp. 153-165 Authors / Editors: (Aderbal S. Aguiar, Jr., Ricardo A. Pinho, Laboratório Experimental de Doenças Neurodegenerativas, Departamento de Farmacologia, Universidade Federal de Santa Catarina (UFSC), Florianópolis-SC, Brazil, and others) |
Chapter 6 - ROLE OF REACTIVE OXYGEN SPECIES IN THE PATHOGENESIS OF AGE-RELATED MACULAR DEGENERATION, pp. 167-196 Authors / Editors: (Suofu Qin, Gerard A Rodrigues, Retinal Disease Research, Department of Biological Sciences, Allergan, Inc., Irvine, CA, USA) |
Chapter 7 - FREE RADICAL PROCESSES IN THYROID CELLS : ROLE OF REACTIVE OXYGEN AND IODINE SPECIES, pp. 197-261 Authors / Editors: (Liliya Nadolnik, Institute of Pharmacology and Biochemistry, National Academy of Sciences of Belarus, Grodno, Belarus) |
Chapter 8 - FREE RADICALS AND HEALTH EFFECTS, pp. 263-289 Authors / Editors: (Fortoul TI, Rodriguez-Lara V, Cano-Gutierrez et al., Department of Cellular and Tissular Biology, School of Medicine, National University of Mexico (UNAM), Mexico City, Mexico) |
Chapter 9 - THE EFFECTS OF SOME SUBSTANCES-PROTECTORS ON FREE-RADICAL HOMEOSTASIS IN DISEASES ASSOCIATED WITH OXIDATIVE STRESS, pp. 291-303 Authors / Editors: (Miguel A.A. Pinheiro de Carvalho, Sergei S. Popov, Olga A. Safonova, Anna V. Makeeva, Larisa V. Matasova, Alexander N. Pashkov, Tatiana N. Popova, ISOPlexis / BIOtexMOL, Center of Macaronesian Studies, Madeira University, Fuchal, Portugal, and others) |
Chapter 10 - THE INVOLVEMENT OF OXIDATIVE STRESS IN EPILEPSY, pp. 305-318 Authors / Editors: (Masaharu Hayashi, Naoyuki Tanuma, Rie Miyata, Department of Clinical Neuropathology, Tokyo Metropolitan Institute for Neuroscience, Tokyo, Japan) |
Chapter 11 - ANTIOXIDANT PROPERTIES OF THIAMINE AND ITS HYDROPHOBIC METABOLITES, pp. 319-376 Authors / Editors: (Stsiapura V.I., Stepuro I.I., Institute of Pharmacology and Biochemistry, National Academy of Sciences of Belarus, Grodno, Belarus, and others) |
Chapter 12 - FREE RADICALS AND PROTEINS - RESEARCH PROGRESS ON SULFUR-CONTAINING PROTEINS UNDER RADICAL STRESS: A HELPFUL CONTRIBUTE FROM RAMAN SPECTROSCOPY, pp. 377-419 Authors / Editors: (Armida Torreggiani, Istituto per la Sintesi Organica e la Fotoreattività (I.S.O.F.), Consiglio Nazionale delle Ricerche (C.N.R.), Bologna, Italy) |
Chapter 13 - METHODOLOGY FOR OXIDATIVE STATE DETECTION IN BIOLOGICAL SYSTEMS, pp. 421-448 Authors / Editors: (Borut Poljšak, Polona Jamnik, University of Ljubljana, Faculty of Heath Studies, Ljubljana, Slovenia, and others) |
Chapter 14 - ROLE OF PLANT EXTRACTS AND POLYPHENOLIC COMPOUNDS IN OXIDATIVE STRESS-RELATED DISEASES, pp. 449-477 Authors / Editors: (Glauce Socorro de Barros Viana, Luzia Kalyne A. Moreira Leal and Juvenia Bezerra Fontenele, Departments of Pharmacy and of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Brazil) |
Chapter 15 - EFFECTS OF PEROXYNITRITE ON MORPHOLOGY AND FUNCTIONS OF NEUTROPHILS, pp. 479-503 Authors / Editors: (Starodubtseva M. N., Kavalenka A. I., Petrenyov D. R., Cherenkevich S. N., Gomel State Medical University, Gomel, Belarus, and others) |
Chapter 16 - LOOKING THROUGH THE MICROSCOPE: WHAT CAN WE LEARN FROM FLUORESCENCE LIFETIME MEASUREMENTS ABOUT FREE RADICALS IN LIVING CELLS ?, pp. 505-521 Authors / Editors: (A-C. Ribou, T. Rharass, J. Vigo) |
Chapter 17 - CARBON NANOPARTICLES IMPACT ON ENERGY METABOLISM, GENOTOXICITY AND FREE RADICALS LEVEL, pp. 523-538 Authors / Editors: (Victor Mikhailenko, Liubomira Ieleiko, Alex Glavin, Julia Sorochinska, Department of Radiobiology and Ecology, R.E.Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology of National Academy of Sciences, Kyiv, Ukraine) |
Chapter 18 - FREE RADICALS: FORMATION, TYPES AND EFFECTS IN CENTRAL NERVOUS SYSTEM, pp. 539-556 Authors / Editors: (Hugo Juárez Olguín, David Calderon Guzman, Laboratorio de Farmacología, Instituto Nacional de Pediatría, Mexico City, Mexico, and others) |
Chapter 19 - ANTIOXIDATIVE AND NEUROPROTECTIVE EFFECTS OF METALLOTHIONEINS ON DOPAMINERGIC NEURONS, pp. 557-568 Authors / Editors: (Ikuko Miyazaki, Masato Asanuma, Department of Brain Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan) |
Chapter 20 - FREE RADICALS INVOLVED IN ULTRASONIC THERAPY, pp. 569-581 Authors / Editors: (Yi Zhang, Tinghe Yu, Yanming Huo, Laboratory of Biomedical Ultrasonics, Institute of Women and Children’s Health, West China Second University Hospital, Sichuan University, Chengdu, China, and others)
***Open Access Chapter. Free Download Available*** |
Chapter 21 - REACTION OF FREE RADICALS OF POLYMER FILMS WITH AMBIENT OXYGEN AS VERIFICATION TOOL OF MECHANISM OF FORMATION OF FILMS FROM HEPTANE IN LOW-TEMPERATURE PLASMA, pp. 583-592 Authors / Editors: (A. M. Lyakhovich, Physicotechnical Institute, Udmurt Scientific Center, Russian Academy of Sciences, Izhevsk, Russia) |
Chapter 22 - FREE RADICAL AND IN VIVO DISEASE CONTROL IN MALARIOLOGY, pp. 593-595 Authors / Editors: (Viroj Wiwanitkit, Wiwanitkit House, Bangkok, Thailand) |
Chapter 23 - FREE RADICAL TEST: A NOVEL TEST IN LABORATORY MEDICINE, pp. 597-600 Authors / Editors: (Viroj Wiwanitkit, Wiwanitkit House, Bangkok, Thailand) |
Chapter 24 - RABIES AND FREE RADICAL: A RELATIONSHIP, pp. 601-603 Authors / Editors: (Viroj Wiwanitkit, Wiwanitkit House, Bangkok, Thailand) |
Series: Cell Biology Research Progress |
Binding: Hardcover |
Pub. Date: 2010 |
Pages: 7 x 10, 642pp. |
ISBN: 978-1-60876-101-2 |
Status: AV |
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