Book Description:
Autoimmune diseases arise from an overactive immune response of the body against substances and tissues normally present in the body. The immune system mistakes some part of the body as a pathogen and attacks it. The treatment of autoimmune diseases is typically with immunosuppression—medication which decreases the immune response. This book presents and reviews important data gathered on autoimmune diseases and related topics such as: systemic lupus erythematosus and nephritis, their diagnosis and management; emerging methods in Type 1 diabetes immunomodulation; blockage of hyperproduced cytokines as a new approach for the treatment of autoimmune conditions; bone marrow transplantation methods for autoimmune/stem cell disorders; the autoimmune attack on myelin proteins which initiate Multiple Sclerosis; and others.

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Table of Contents:
Preface

Natural Catalytic Antibodies in Norm and in Autoimmune Diseases;pp. 1-106
(G. A. Nevinsky, Institute of Chemical Biology and Fundamental Medicine of Siberian Division of Russian Academy of Sciences, Novosibirsk, Larentieva, Russia)

Lupus Nephritis: Frontiers and Challenges-A Comprehensive Overview;pp. 107-165
(Hussein A. Sheashaa, Tarek M. Abbas, Fatma E. Moustafa, Khaled Mahmoud, Amgad el-Agroudy, Anil Chandraker, Nidyanandh Vadivel, Rashad Hassan , Ashraf M. Bakr, Mohamed Zedan, Noha Tharwat, Wael I. Elkady, Helmut G. Rennke, Mohamed Sobh, Urology and Nephrology Center, Mansoura University, Egypt, and others)

From Immunobiology to Genetics: In Search of a Cure for Autoimmunity;pp. 167-208
Sylvie Lesage, Erin Hillhouse, Véronique Dugas, Geneviève Chabot-Roy, Adam-Nicolas Pelletier, Marie Vilquin, Fanny Guimont-Desrochers,
University of Montreal, Department of Microbiology and Immunology, Montreal, Quebec, Canada, and others)

Central Nervous System Manifestations in Systemic Lupus Erythematosus: Diagnosis to Treatment;pp. 209-231
(Simone Appenzeller, Mariana Postal, State University of Campinas (UNICAMP), Campinas-SP-Brazil, and others)

Emerging Methods in Type 1 Diabetes Immunomodulation: Beyond the Conventional;pp. 233-249
(Brett E. Phillips, Nick Giannoukakis, Department of Pathology, Rangos Research Center, Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania)

Lupus Nephritis: From Diagnosis to Treatment;pp. 251-264
(Nailú Angélica Sinicato, Mariana Postal, Simone Appenzeller, Rheumatology Unit - State University of Campinas (UNICAMP), Campinas-SP-Brazil, and others)

Clinical Features of Axonal Guillain–Barré Syndrome;pp. 265-276
(Akiyuki Hiraga, Masahiro Mori, Satoshi Kuwabara, Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan, and others)

Removal [Blockage] of Hyperproduced Cytokines - A New Approach to the Treatment of Autoimmune Conditions;pp. 277-288
(Simon V. Skurkovich)

Revolutionary Bone Marrow Transplantation Method for Stem Cell Disorders;pp. 289-302
(Susumu Ikehara, First Department of Pathology, Regeneration Research Center for Intractable Diseases, Kansai Medical University, Moriguchi City, Osaka, Japan)

Immunological Control of Adult Neural Stem Cells;pp. 303-316
(Oscar Gonzalez-Perez, Alfredo Quiñones-Hinojosa, Jose Manuel Garcia-Verdugo, Neuroscience Laboratory, Psychology School, University of Colima, Colima, Mexico, and others)

Temporomandibular Joint Disorders and Systemic Lupus Erythematosus;pp. 317-327
(Andre L. F. Costa, Simone Appenzeller, Faculty of Medical Science, State University of Campinas (UNICAMP), Campinas, Brazil, and others)

Fatigue in Guillain-Barré Syndrome: Activity-Dependent Conduction Block;pp. 329-339
(Hiroyuki Nodera, Atsuko Nodera, Department of Neurology and Neuroscience, Weill Cornell Medical College, New York, NY, USA, and others)

Could Computerized Devices for Optic Nerve Head Analysis Find Out Loss of Ganglion Cells in Not-Glaucomatous Damage?;pp. 341-348
(Michele Iester, Marina Papadia, Alessandra Bagnis, Laboratorio Clinico Anatomo-funzionale Per La Diagnosi e Il Trattamento del Glaucoma e Delle Malattie Neuro-oftalmologiche, Clinica Oculistica, Department of Neurological Sciences, Ophthalmology, Genetic, University of Genoa, Italy)

Structural biology insights into the autoantigens of the myelin sheath;pp. 349-367
(Petri Kursula, Department of Biochemistry, University of Oulu, Oulu, Finland and CSSB-HZI, DESY, Hamburg, Germany)

Autoimmune Initiation of Multiple Sclerosis: Molecular Aspects;pp. 369-402
(Fred C. Westall, Institute for Disease Research, Temecula, California)*

Genetic Control of T Cell Tolerance and Susceptibility to Autoimmune Disease;pp. 403-435
(Lydia Makaroff, Michelle Linterman, Adrian Liston, Department of Immunology, University of Washington, Seattle, Washington, and others)*

Index pp.437-465