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Handbook of Prenatal Diagnosis: Methods, Issues and Health Impacts
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Editors: Elian Pereira and Juliano Soria
Book Description:
Prenatal diagnosis is a method to detect fetal disease before delivery. Ideally, prevention of fetal exposure to harmful influences begins before conception because all major organ systems develop early in pregnancy, often before a woman realizes that she is pregnant. Prenatal diagnosis is composed of non-invasive and invasive methods. This book summarizes recent developments in the field of non-invasive prenatal diagnosis (NIPD) through the use of fetal cells and ffDNA in maternal circulation during pregnancy and provides an overview of the possibilities for future clinical applications. The various options for prenatal screening for Down Syndrome (DS) is also outlined, in addition to current research efforts made to improve non-invasive prenatal diagnosis based on fetal cells, cell free fetal DNA and proteins present in maternal circulation. Additionally, this book gives an overview of essential aspects of primary prevention efforts and effecting factors including age and socio-demographical factors, obstetric history, maternal medical conditions, genetic disorders, psycho-social issues and infections and vaccination. Other chapters in this book discuss the close correlation between hypertensive dysfunction in pregnancy and the development of cardiovascular diseases, the various techniques and applications of MRI in fetal imaging, a review of prenatal genetic diagnosis (PGD), the relation between antithrombin congenital deficiency and high risk miscarriages and recurrent abortions, and a review of literature on arthrogryposis multiplex congenita, the occurrence of multiple joint contractures at birth.

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Table of Contents:

Prevention of Congenital Anomalies and the Roles of Healthcare Professionals, pp. 1-39
(Nevin Hotun Sahin, İlkay Gungor, Istanbul University Florence Nightingale School of Nursing, Department of Obstetric and Gynecologic Nursing, Istanbul, Turkey)

Progress in Non-Invasive Prenatal Diagnosis from Fetal Cells and Free Fetal DNA, pp. 41-62
(Kolialexi Aggeliki, Tounta Georgia, Kouvidi Elisavet and Mavrou Ariadni, Department of Medical Genetics, Athens University School of Medicine, Athens, Greece)

Prenatal Diagnoses: Reason for Technique and Issue, pp. 63-93
(Vorapong Phupong, Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand)

How Does Prenatal Diagnosis Contribute to the Prevention of Myelomeningocele in Iran, pp. 95-114
(Nima Baradaran, Farideh Nejat, Mostafa El Khashab, Children’s Hospital Medical Center, Tehran University of Medical Science, Tehran, Iran and others)

Techniques Used in Rapid Aneuploidy Detection in Prenatal Diagnosis: A Comparison of Fluorescence in situ Hybridization (FISH) with Molecular Genetic Methods, pp. 115-133
(Jia-Chi Wang, Cytogenetics Laboratory, Hamilton Regional Laboratory Medicine Program, Hamilton Health Sciences, Hamilton, Ontario, Canada

Advances in Prenatal Screening for Down Syndrome, pp. 135-149
(Aggeliki Kolialexi, Georgia Tounta, Nikolas Papantoniou, George Th. Tsangaris and Ariadni Mavrou, Department of Medical Genetics, Athens University, School of Medicine, Athens, Greece and others)

Cell-Free Fetal DNA in Maternal Circulation towards Non-Invasive Prenatal Diagnosis of β-Thalassemia, pp. 151-163
(Thessalia Papasavva and Marina Kleanthous, Molecular Genetics Thalassaemia Department, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus)

Cerebral Hemodynamics in Pregnancy by Doppler Sonography;pp. 165-179
(Renato A. Moreira De Sa, Fernanda Campos da Silva, Cristiane Alves de Oliveira, Grupo Perinatal, Universidade Federal Fluminense - UFF, Rio de Janeiro, Brazil)

Arthrogryposis Multiplex Congenita, pp. 181-199
(Banu Dane, Cem Dane, Haseki Training and Research Hospital, Department of Gynecology and Obstetrics, Istanbul, Turkey)

Confounding of Genetic and Environmental Factors in Pregnancy-Induced Hypertension, pp. 201-216
(Gen Kobashi, Department of Global Health and Epidemiology, Hokkaido University Graduate School of Medicine, Sapporo, Japan and others)

Fetal MRI, pp. 217-231
(Manjiri Dighe, Department of Radiology, University of Washington Medical Center, Seattle, WA)

Hyperoxygenation Study as a Predictor of Neonatal Outcome in Congenital Cystic Adenomatous Malformations, pp. 233-244
(Kristin Riley, Neil S. Seligman, Dennis C. Wood, Kevin Dysart, Stuart Weiner, Department of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, PA and others)

Borderline Width of Fetal Lateral Cerebral Ventricular Atrium: Our Experience, pp. 245-253
(J. Piazze, A. Spagnuolo, A. Cerekja, A. Giancotti, Department of Gynecology, Perinatology and Child Health, University of Rome “La Sapienza”, Rome, Italy)

Cardiovascular Risk Following Hypertensive Pregnancy, pp. 255-269
(Giancarlo Paradisi, Terryann Spagnuolo, Francesca Ianniello, Marina Bracaglia, Antonietta Labianca, Lorena Quagloiozzi, Augusto Di Vico, Alessandro Caruso, Department of Obstetrics & Gynecology, Universita Cattolica del Sacro Cuore-Policlinico Agostino Gemelli, Rome, Italy)

Fetal Hemodynamic Assessment from the Relationship between Fetal Aortic Diameter Pulse and Flow Velocity Waveforms during Fetal Development, pp. 271-279
(Akira Mori, Akane Kondo, Masaya Watada, Department of Medical Engineering, Tokyo City University, Tokyo, Japan, and others.)

Low Birth Weight is a Risk Factor for Cardiovascular Disease, pp. 281-286
(Peter J. Giannone, Juli M. Richter, John A. Bauer, Nationwide Children’s Hospital, Center for Cardiovascular and Pulmonary Research, Columbus, OH)

An Ethical Insight on the New Trends in Prenatal Genetic Diagnosis, pp. 287-293
(Carlo Bellieni, Giuseppe Buonocore, Department of Pediatrics, Obstetrics, and Reproduction Medicine, University of Siena, Italy)

Antenatal Diagnosis of Umbilical Cord Cysts: A 5-Year Experience and Review of the Literature, pp. 295-300
(Juan C. Villa, Nancy W. Hendrix, and Stuart Weiner, Department of Obstetrics & Gynecology, Division of Maternal Fetal Medicine, Thomas Jefferson University, Philadelphia, PA)

Reliability of Three-Dimensional Ultrasound Measurement of Hourly Fetal Urine Production Rate, pp. 301-307
(Renato A. Moreira De Sa, Fernando Maia Peixoto-Filho, Carolina C. Mocarzel, Laudelino M. Lopes and L.G.C. Velarde, Grupo Perinatal, Universidade Federal Fluminense - UFF, Rio de Janeiro, Brazil)

Fetal Anemia at Term with Persistent Negative Maternal Indirect Coombs Tests, pp. 309-312
(J. Piazze, P. Meloni, A. Cerekja, F. Reccia, E.V. Cosmi, Institute of Gynecology, Perinatology and Child Health, University "La Sapienza", Rome, Italy and others)

Transvaginal Ultrasound, Hysterosonography and Hysteroscopy in the Monitoring of Tamoxifen Treated Breast Cancer Patients: Which is Better?, pp. 313-316
(J. Piazze, A. Cerekja, S. Rea. M. Buccheri, S. Martiello, R. La Torre, Department of Gynecology, Perinatology and Child Health, University of Rome “La Sapienza”, Ceprano Hospital, Ultrasound Division, Rome Italy)

Antithrombin Congenital Deficiency in Pregnancy, pp. 317-320
(J. Piazze, A. Giancotti, A. Spagnuolo, A. Cerekja, Institute of Gynecology, Perinatology and Child Health, University “La Sapienza”, Rome, Italy and others)

Molecular Testing for Prenatal Diagnosis: Current Practice and Emerging Techniques, pp. 321-331 (Andrew H. Beck and Iris Schrijver, Departments of Pathology and Pediatrics, Stanford University School of Medicine, Stanford, CA, USA)

Management of Pregnant Women with Complete Atrioventricular Block, pp. 333-353
(Nobuhiro Hidaka and Yoshihide Chiba, Kyushi University,Fukuoka, Japan. Chiba Womens's Clinic,Osaka, Japan)


      Pregnancy and Infants: Medical, Psychological and Social Issues
   Binding: Hardcover
   Pub. Date: 2010
   Pages: 7 x 10, 379 pp.
   ISBN: 978-1-60741-254-0
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
Special Focus Titles
01.Violent Communication and Bullying in Early Childhood Education
02.Cultural Considerations in Intervention with Women and Children Exposed to Intimate Partner Violence
03.Chronic Disease and Disability: The Pediatric Lung
04.Fruit and Vegetable Consumption and Health: New Research
05.Fire and the Sword: Understanding the Impact and Challenge of Organized Islamism. Volume 2

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Handbook of Prenatal Diagnosis: Methods, Issues and Health Impacts