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Bioencapsulation in Silica-Based Nanoporous Sol-Gel Glasses
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Authors: Bouzid Menaa, Farid Menaa, and Olga Sharts (Fluorotronics, Inc. San Diego Technology Incubator, San Diego, CA) 
Book Description:
In this book, the authors report the recent results on the influence of different parameters (such as surface hydration, hydrophobicity, solute effects, thermal stability, porosity, macromolecular crowding) on the protein conformation based on the design and the characterization of nanoporous silica-based materials containing different functional groups (e.g., hydrophobic alkyl, phosphate and fluorinated groups). The enhancement of the protein folding owing the physical properties and microstructure of the host matrix induced by the nature of the functional groups and the siloxane network play a major role on the protein biological activity and therefore to the development efficient bionanodevices such as biocatalysts, sensors, drug delivery systems or implanted devices. This book enlightens the bioapplications of silica-based glasses prepared from functionalized organosilane precursors used to mimic and to understand the different factors that influencing the protein folding process.



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Table of Contents:
Preface
Abstract

Chapter 1. INTRODUCTION, pp. 1-4

Chapter 2. SOL-GEL BIOENCAPSULATION PROCESS IN SILICA-BASED MATERIALS: METHOD, MATERIALS AND BIOAPPLICATIONS, CHARACTERIZATION TECHNIQUES, pp. 5-18

Chapter 3. PARAMETERS AFFECTING THE PROTEIN FOLDING IN NANOPOROUS SILICA-BASED SOL-GEL GLASSES, pp. 19-38

Chapter 4. ENHANCING THE PROTEIN FOLDING BY INTRODUCING AND ASSOCIATING HYDROPHOBIC AND STERIC EFFECTS IN MODIFIED SILICA-BASED POROUS GLASSES, pp. 39-42

Chapter 5. DEVELOPED TECHNIQUES FOR A BETTER UNDERSTANDING OF PROTEIN FOLDING IN NANOPOROUS SOL-GEL GLASSES, pp. 43-46

Conclusion
References
Index

   Series:
      Nanotechnology Science and Technology
   Binding: Softcover
   Pub. Date: 2011
   Pages: 6 x 9
   ISBN: 978-1-60876-989-6
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Bioencapsulation in Silica-Based Nanoporous Sol-Gel Glasses