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Nerve Growth Factor and Pain
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Authors: Paola Sarchielli, Katiuscia Nardi, Stefano Caproni, Davide Chiasserini, Alessio Pieroni, Ilenia Corbelli and Paolo Calabresi, (University of Perugia, Italy and others) 
Book Description:
Nerve growth factor (NGF) has a key role not only in the development of sensory and autonomic neurons, but also in the processes of nociception. Several central and peripheral mechanisms have been postulated as the basis of effects of NGF in nociceptive pathways. It has been implicated both in inflammatory and neuropathic pain mechanisms and strategies against NGF, its receptors, and down-stream intracellular signaling activated by this neurotrophin (NT) have been proposed for the treatment of these pathological conditions. This new book examines recent evidence of the involvement of NGF in painful diseases and suggests the potential usefulness of anti-NGF strategies as novel analgesics for these disabling pathological conditions.

Table of Contents:
INTRODUCTION, pp. 1-2

NGF AND NOCICEPTION, pp. 3-4

INTRACELLULAR MECHANISMS OF NGF ACTION, pp. 5-8

PATHOPHYSIOLOGICAL MECHANISMS OF INFLAMMATORY AND NEUROPATHIC PAIN, pp. 9-12

EXPERIMENTAL EVIDENCE FOR THE INVOLVEMENT OF NGF IN INFLAMMATORY AND NEUROPATHIC PAIN, pp. 13-20

PATHOPHYSIOLOGICAL MECHANISMS OF MIGRAINE, pp. 21-24

PATHOPHYSIOLOGY OF FIBROMYALGIA, pp. 25-26

INVOLVEMENT OF NGF IN THE PATHOPHYSIOLOGICAL MECHANISMS OF MIGRAINE AND FIBROMYALGIA, pp. 27-32

POTENTIAL OF NGF TARGETING STRATEGIES IN NEUROPATHIC PAIN, CHRONIC MIGRAINE AND FIBROMYALGIA, pp. 33-38

CONCLUSIONS, 39-59

INDEX

   Series:
      Pain and its Origins, Diagnosis and Treatments
   Binding: Softcover
   Pub. Date: 2011
   Pages: 6 x 9
   ISBN: 978-1-61668-264-4
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Nerve Growth Factor and Pain