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Protein Aggregation
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Editors: Douglas A. Stein
Book Description:
Protein aggregation is the aggregation of mis-folded proteins, and is thought to be responsible for many degenerative diseases, such as Alzheimer's. This book presents current research from across the globe in the study of protein aggregation, including the processes of protein aggregation induced by freezing and lyophilization; functional amyloids; thermally induced aggregation of a model system protein - insulin; the aggregation of albumin; synucleins implicated in neurodegenerative diseases and some forms of cancer; yeast protein aggregates; and the folding and aggregation features of proteins. (Imprint: Nova Biomedical)

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Chapter 1 - Changes in Protein Structure under the Effects of Cryopreservation and Cryoprotective Agents pp. 1-39
Authors / Editors: (N.G. Zemlianskykh, Institute for Problems of Cryobiology and Cryomedicine of NAS of Ukraine, Kharkiv, Ukraine)

Chapter 2 - Molecular Chaperones and Proteases as Suppressors of Protein Aggregation in Gram-Negative Bacteria pp. 41-77
Authors / Editors: (Joanna Skorko-Glonek, Dorota Kuczynska-Wisnik, Dorota Zurawa-Janicka, Ewelina Matuszewska, Donata Figaj, Barbara Lipinska, University of Gdansk, Department of Biochemistry, Kladki, Gdansk, Poland)

Chapter 3 - Native Functions of Amyloid pp. 79-109
Authors / Editors: (Reeba S. Jacob, A. Anoop, Pradeep K. Singh, Samir K. Maji, Department of Biosciences and Bioengineering, IIT Bombay, Powai, Mumbai, India)

Chapter 4 - Nucleation Mechanisms and Morphologies in Insulin Amyloid Fibril Formation pp. 111-137
Authors / Editors: (Vito Foderà, Fabio Librizzi, Valeria Militello, Giovanna Navarra, Valeria Vetri and Maurizio Leone, Dipartimento di Scienze Fisiche e Astronomiche, Università degli Studi di Palermo, Palermo, Italy)
***Open Access Chapter. Free Download Available***

Chapter 5 - On the Aggregation of Albumin: Influences of the Protein Glycation pp. 139-159
Authors / Editors: (Philippe Rondeau, Giovanna Navarra, Valeria Militello, Emmanuel Bourdon, Laboratoire de Biochimie et Génétique Moléculaire (LBGM), Groupe d’Etude sur l’Inflammation Chronique et l’Obésité (GEICO), Université de La Réunion, Saint Denis de La Réunion, France, and others)
***Open Access Chapter. Free Download Available***

Chapter 6 - The Role of Conformational Domain Lability of Fibrinogen Molecules in Processes of Self-Assembly of Fibrin Monomers and Fibrinogen Aggregation pp. 161-178
Authors / Editors: (M.A. Rosenfeld, V.B. Leonova, M.I. Biryukova, Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russia)

Chapter 7 - Two Faced Members of the Family: The Synucleins pp. 179-192
Authors / Editors: (Andrei Surguchov, VA Medical Center Kansas City, Kansas City, Missouri, USA and Kansas University Medical Center, Kansas)
***Open Access Chapter. Free Download Available***

Chapter 8 - Inclusion Bodies: A New Concept of Biocatalysts pp. 193-198
Authors / Editors: (Neus Ferrer-Miralles, Mónica Martínez-Alonso, Antonio Villaverde, Elena García-Fruitós, Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, Barcelona, Spain, and others)

Chapter 9 - Comparative Study of Bovine and Ovine Caseinate Aggregation Processes: Calcium-Induced Aggregation and Acid Aggregation pp. 199-222
Authors / Editors: (María Eugenia Hidalgo, Manuel A. Mancilla Canales, Cássia R. Nespolo, Anselmo D. Reggiardo, Estela M. Alvarez, Jorge R. Wagner, Patricia Risso, Departamento de Química-Física, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, (2000) Rosario, Argentina, and others)

Chapter 10 - Protein Aggregation pp. 223-235
Authors / Editors: (Xiaoyu Lu, Yan Wei, Rongqiao He, State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China)
***Open Access Chapter. Free Download Available***

Chapter 11 - Yeast Protein Aggregates, Containing Chaperones and Glucose Metabolism Enzymes pp. 237-265
Authors / Editors: (O.V. Nevzglyadova, A.V. Artemov, A.G. Mittenberg, E.V. Mikhailova, I.M. Kuznetsova, K.K. Turoverov, T.R. Soidla, Institute of Cytology, St. Petersburg, Russia)

Chapter 12 - Folding and Aggregation Features of Proteins pp. 267-279
Authors / Editors: (OxanaV. Galzitskaya, Sergiy O. Garbuzynskiy, Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region, Russian Federation)

      Protein Science and Engineering
      Microbiology Research Advances
   Binding: Hardcover
   Pub. Date: 2011
   Pages: 298.pp
   ISBN: 978-1-61761-815-4
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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Protein Aggregation