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Regulatory T Cells
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Editors: Ren S. Hayashi
Book Description:
Regulatory T cells (sometimes known as suppressor T cells) are a specialized subpopulation of T cells that act to suppress activation of the immune system and thereby maintain immune system homeostasis and tolerance to self-antigens. This book presents topical research in the study of regulatory T cells, including the role of regulatory T cells in the treatment of multiple sclerosis and hepatocellular carcinoma; genetic engineering of antigen-specific regulatory T cells; regulatory T cells in arthritis, allergic disorders and immunomodulation; and the roles of immunoregulatory cells and the mechanisms of immune response.
(Imprint: Nova Biomedical)

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Chapter 1 - T Helper 17 Cells Interplay with CD4+CD25highFoxp3+ Regulatory T Cells in Regulating Autoimmune Inflammation, pp. 1-32
Authors / Editors: (Jietang Mai, Anthony Virtue, Hong Wang, Xiao-Feng Yang, Department of Pharmacology, Cardiovascular Research Center, Temple University School of Medicine, Philadelphia, Pennsylvania, USA)
***Open Access Chapter. Free Download Available***

Chapter 2 - Human CD8 Tregs as Contenders in Chronic Persisting Infections, pp. 33-56
Authors / Editors: (Simone A. Joosten, Tom H. M. Ottenhoff, Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands)

Chapter 3 - Role of Regulatory T Cells in the Treatment of Multiple Sclerosis, pp. 57-78
Authors / Editors: (K. Szklany, T.C. Koehler, W. van Eden, Utrecht University, The Netherlands)

Chapter 4 - Immunoregulatory Cells and Mechanisms of Immune Response, pp. 79-97
Authors / Editors: (Carol Aristimuño, Roseta Teijeiro, Clara de Andrés, Silvia Sánchez-Ramón, Department of Immunology and Neurology, Hospital General Universitario Gregorio Marañón, Madrid, Spain)

Chapter 5 - Roles of Regulatory T Cells in Oral Tolerance and Food Allergy, pp. 99-116
Authors / Editors: (Yusei Ohshima, University of Fukui, Yoshida-gun Fukui, Japan)

Chapter 6 - The Role of Regulatory T Cells in GVL and GVHD, pp. 117-135
Authors / Editors: (Abdullah Alsuliman, Paula Garland, Katayoun Rezvani, Imperial College, Hammersmith Campus, London, United Kingdom)

Chapter 7 - Regulatory T Cells and Hepatocellular Carcinoma: Implication of the Regulatory T Lymphocytes in the Control of the Immune Response, pp. 137-168
Authors / Editors: (Nadira Delhem, Céline Miroux, Thibaut Vausselin, Laboratoire d’Immunopathologie des Cancers Viro-Induits, Institut de Biologie de Lille, Lille, France)

Chapter 8 - Regulatory T cells and Tumor Immunity in the Tumor Microenvironment, pp. 153-168
Authors / Editors: (Lisong Shen, Matthew R. Thompson, Dakang Xu, Department of Clinical Laboratory, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China, and others)

Chapter 9 - Advantages and Disadvantages of and Cooperation between CD8+ and CD4+ Regulatory T Cells, pp. 169-183
Authors / Editors: (Haruhiko Suzuki, Yusuke Okuno, Agustina Tri Endharti, Department of Immunology, Nagoya University Graduate School of Medicine, Nagoya, Japan, and others)
***Open Access Chapter. Free Download Available***

Chapter 10 - Regulatory T Cells in Arthritis: Why Do they Fail?, pp. 185-199
Authors / Editors: (Halima Moncrieffe, Lucy R. Wedderburn, Rheumatology Unit, Institute of Child Health, University College London, London, United Kingdom)

Chapter 11 - Immune Homeostasis Maintained by Tregs, pp. 201-223
Authors / Editors: (Myoung-Ho Jang, Yun-Jae Jung, Hyung-Ran Kim, Byung-In Moon, Ju-Young Seoh, Laboratory of Gastrointestinal Immunology, World Premier International Immunology Frontier Research Center, Osaka University, Osaka, Japan, and others)
***Open Access Chapter. Free Download Available***

Chapter 12 - Regulating FOXP3 by Cis Elements, pp. 225-237
Authors / Editors: (Peter C.J. Janson, Ola Winqvist, Department of Medicine, Clinical Allergy Research Unit, Karolinska Institutet, Stockholm, Sweden)
***Open Access Chapter. Free Download Available***

Chapter 13 - Genetic Engineering of Antigen-Specific Regulatory T Cells, pp. 239-246
Authors / Editors: (Eran Elinav, Zelig Eshhar, Section on Immunobiology, Yale University School of Medicine and Department of Immunology, The Weizmann Institute, Rehovot, Israel)

Chapter 14 - Regulatory T Cells in Allergic Disorders and Immunomodulation, pp. 247-250
Authors / Editors: (Kei-ichi Yamanaka, Department of Dermatology, Mie University, Graduate School of Medicine, Edobashi, Tsu, Mie, Japan)

Chapter 15 - The Number of Regulatory T Cells: Pursuit of the Golden Mean, pp. 251-268
Authors / Editors: (Alexander Pukhalsky, Galina Shmarina, Vladimir Alioshkin, Research Centre for Medical Genetics, Moscow, Russia, and others)
***Open Access Chapter. Free Download Available***

      Cell Biology Research Progress
      Immunology and Immune System Disorders
   Binding: Hardcover
   Pub. Date: 2011
   Pages: 7 x 10 (NBC - R)
   ISBN: 978-1-61761-554-2
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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Regulatory T Cells