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Gold Nanoparticles as an Antigen Carrier and an Adjuvant
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Authors: L. A. Dykman, S. A. Staroverov, V. A. Bogatyrev and S. Yu. Shchyogolev (Russian Academy of Sciences, Saratov, Russia) 
Book Description:
This book summarizes known data and the results of the authors’ own
investigations into the use of gold nanoparticles as an antigen carrier and as an adjuvant in immunization for in vivo preparation of antibodies. Many kinds of biologically active substances have relatively low molecular masses and, as a rule, evoke weak immune responses. For overcoming this restriction, in standard antibody-production techniques, haptens are chemically bound to high molecular-mass carriers, allowing preparation of a specific enough, hightiter antiserum. However, such an antiserum usually contains concomitant antibodies to the carrier’s epitopes. This new book presents a technology for production of antibodies against various antigens by using colloidal gold as a carrier and as an adjuvant.

Table of Contents:
Preface

Chapter I. Introduction, pp. 1-6

Chapter II. Adjuvant Properties of Gold Nanoparticles, pp. 7-25

Chapter III. Conclusions, pp. 27-29

Acknowledgments
References
Index

   Series:
      Nanotechnology Science and Technology
   Binding: Softcover
   Pub. Date: 2010
   Pages: 6 x 9
   ISBN: 978-1-61668-771-7
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Gold Nanoparticles as an Antigen Carrier and an Adjuvant