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Immunogenetics: Tolerance and Autoimmunity
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Authors: Sylvie Lesage (University of Montreal, Montreal, Canada) 
Book Description:
The Human Genome Project has facilitated the identification of various genetic regions associated with disease susceptibility. This identification step is important as it yields clues into the pathways implicated in defining disease susceptibility and may uncover important therapeutic targets. Indeed, by performing genome-wide scans, one can identify many genetic loci associated with autoimmune disease susceptibility. However, the odds ratio of each locus is relatively low. Therefore, the limitation of these studies is in the biological translation of the data. This raises the question of how one verifies the true biological impact that each of these genetic variations has on human disease. This book presents an alternative strategy for the identification of various genetic regions associated with disease susceptibility.
(Imprint: Nova Biomedical)




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Table of Contents:
Chapter 1: Determining Genetic Susceptibility;pp. 1-10

Chapter 2: T Cells;pp. 11-25

Chapter 3: B Cells;pp. 27-35

Chapter 4: Dendritic Cell Subsets;pp. 37-46

Chapter 5: Macrophages;pp. 47-54

Chapter 6: Natural Killer Cells;pp. 55-67

Concluding Remarks;pp. 69-70

Abbreviation List

Index

   Series:
      Cell Biology Research Progress
      Genetics - Research and Issues
   Binding: Softcover
   Pub. Date: 2010 4th quarter
   Pages: 6 x 9, 77pp.
   ISBN: 978-1-61761-478-1
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Immunogenetics: Tolerance and Autoimmunity