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Vitamin A and Lung Development
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Authors: M. L. Pinto, P. Rodrigues (University of Trás-os-Montes e Alto Douro, Vila Real, Portugal), A. Honório, C. Gonçalves and V. Bairos (University of Coimbra, Portugal) 
Book Description:
Lung development is a methodical and coordinated process that culminates in the creation of an organ that contains airways, alveoli, blood vessels, multiple innate and acquired host defense systems, and processes to weaken the harmful effects of oxygen in the environment. By regulating cellular differentiation and branching morphogenesis, vitamin A plays an essential role during lung development. Retinoic acid is required for normal alveolar development and vitamin A administration increases lung’s elastic fiber contents at birth. Additionally, several experiments showed that retinoic acid restores alveolar architecture to dexamethasone-treated lungs and maintains alveolar development in lungs treated with an angiogenic inhibitor. This book discusses and presents data on vitamin A and its role in lung development. (Imprint: Nova Biomedical)

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Table of Contents:
1. Introduction1-2

2. Stages of Lung Development;pp. 3-6

3. Vitamin A Signaling Pathways during the Early Stages of Lung Development;pp. 7-10

4. Vitamin A Signaling Pathways during Lung Maturation;pp. 11-20

5. Biometric and Morphological Data from Lungs Developed under the Influence of Vitamin A;pp. 21-26

6. Vitamin A and Lung’s Elastic Fibers;pp. 27-32

7. Vitamin A and Its Derivatives during Gestation and in the Postnatal Period;pp. 33-44
8. Vitamin A and Its Derivatives in the Adult;pp. 45-54

9. Lessons from Lung Injury Animal Models and Therapeutic Interventions with Vitamin A;pp. 55-58

10. Conclusion;pp. 59-60

References pp.61-72

Index pp.73-77

   Series:
      Public Health in the 21st Century
      Nutrition and Diet Research Progress
   Binding: Softcover
   Pub. Date: 2011
   Pages: 77.pp
   ISBN: 978-1-61761-311-1
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Vitamin A and Lung Development