Book Description:
Metabolism represents a complex system characterized by a high variability in metabolites’ structure, concentration and regulation ratio. Such a variability is observed at different metabolic scales going from metabolites to metabolic profiles via chemical reactions and metabolic pathways, as well as under static or dynamic aspects. Variations in these components are due to apparition-disappearance, level increase-decrease and/or relative changes in weights or contributions leading to different structural, functional and evolutive states of the metabolic system. This book presents a variety of different computational approaches of the variability in metabolic systems. (Imprint: Nova Biomedical)

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Table of Contents:
Introduction

Chapter 1. Multiple Classification of Metabolomic Approaches, pp. 7-36

Chapter 2. Stoichiometry-Based Approaches, pp. 37-53

Chapter 3. Correlation-Based Approaches, pp. 55-111

Chapter 4. Distances- and Similarity Indices-Based Approaches: Cluster Analysis, pp. 113-134

Chapter 5. Outliers and Extreme Cases Analysis, pp. 135-156

Chapter 6. Weighted Metabolic Profiles Analysis, pp. 157-173

Chapter 7. Time-Dependent Analysis of Metabolic Systems, pp. 175-232

Index