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Cocaine's Impact on Affect, Activity, and Reward are Dose-Dependently Impacted by Age
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Editors: Brian M. Kelley, Candace E. Perry, Hillary A. Hershey and Adrianna L. Baird (Bridgewater College, Bridgewater, VA, USA)
Book Description:
This book examines the impact of different doses of cocaine on three interrelated measures related to affective behaviors between adolescent and adult mice in order to assess the range of affective and rewarding responses, measure of despair, activity, and reward were used. Such methods included the forced swim test (FST), motor activity (MA), and the conditioned place preference (CPP) tests, respectively. Cocaine was selected, in part, because of its robust psychostimulant properties, its use by millions of substance abusers worldwide, and its well understood mechanism of action. This study may help explain some of the neurobiological underpinnings of these finding because cocaine was especially effective in reducing despair-related behavior in adolescence compared with adults, yet less effective in as an euphoric agent. (Imprint: Nova Biomedical Press)



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Table of Contents:
CHAPTER 1. INTRODUCTION, pp. 1-6

CHAPTER 2. METHODS, pp. 7-12

CHAPTER 3. RESULTS, pp. 13-19

CHAPTER 4. CONCLUSION, pp. 21

CHAPTER 5. DISCUSSION, pp. 23-38

INDEX

   Series:
      Substance Abuse Assessment, Interventions and Treatment
   Binding: Hardcover
   Pub. Date: 2011
   Pages: 5.5 x 8.5 (NBC - C)
   ISBN: 978-1-61122-744-4
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Cocaine's Impact on Affect, Activity, and Reward are Dose-Dependently Impacted by Age