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Hepatic Insulin Resistance and Nonalcoholic Fatty Liver Disease
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Authors: Marcia Barbosa Aguila, Caroline Fernandes-Santos, Alessandra Da Rocha Pinheiro-Mulder, Tatiane Da Silva Faria and Carlos Alberto Mandarim-De-Lacerda (University of Rio de Janeiro, Brazil) 
Book Description:
Insulin resistance (IR) and metabolic syndrome are associated with the pathogenesis and progression of non-alcoholic fatty liver disease (NAFLD). It encompasses a spectrum of hepatic pathology, ranging from simple steatosis in its most benign form (fatty liver), going through nonalcoholic steatohepatitis (NASH) in its intermediate form, until cirrhosis and hepatocellular carcinoma, its most advanced forms. This new book presents current research on the background of fatty acid oxidation; hepatic steatosis and its progression to NASH and cirrhosis; fibrosis and myofibroblastic cells differentiation; methods of diagnosis; clinical features and laboratory tests and, finally, rodent NAFLD and NASH models. (Imprint: Nova Biomedical Press)



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Table of Contents:
Introduction

1. Triglyceride Storage Regulation in Hepatocytes;pp. 3-5

2. Impairment of Fatty Acid Oxidation;pp. 7-8

3. NAFLD and Its Progression to NASH and Cirrhosis;pp. 9-11

4. Steatosis;pp. 13-16

5. Inflammation;pp. 17-20

6. Fibrosis and Myofibroblastic Cell Differentiation;pp. 21-26

7. Methods of Diagnosis;pp. 27-40

8. Rodent NAFLD and NASH Models;pp. 41-47

9. Conclusions;pp. 49

References;pp. 51-71

Index

   Series:
      Hepatology Research and Clinical Developments
   Binding: Softcover
   Pub. Date: 2011
   Pages: 6 x 9 (NBC - C) 85pp.
   ISBN: 978-1-61209-528-8
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Hepatic Insulin Resistance and Nonalcoholic Fatty Liver Disease