Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
  Top » Catalog » Books » My Account  |  Cart Contents  |  Checkout   
Quick Find
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
Fetal Alcohol Syndrome: Recognition, Differential Diagnosis and Long-Term Effects
Shopping Cart more
0 items
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Notifications more
NotificationsNotify me of updates to Serpins and Protein Kinase Inhibitors: Novel Functions, Structural Features and Molecular Mechanisms
Tell A Friend
Tell someone you know about this product.
Serpins and Protein Kinase Inhibitors: Novel Functions, Structural Features and Molecular Mechanisms $265.00
Editors: Bojidor Georgiev and Sava Markovski
Book Description:
Serpins, a group of proteins with similar structures, were first identified as a set of proteins able to inhibit proteases. The first members of the serpin superfamily to be extensively studied were the human plasma proteins antithrombin and antitrypsin, which play key roles in controlling blood coagulation and inflammation. Today, over 1000 serpins have been identified, including 36 human proteins, as well as molecules in plants, fungi, bacteria, archaea and certain viruses. Serpins are thus the largest and most diverse family of protease inhibitors. In contrast, a protein kinase inhibitor is an enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation). Protein tyrosine kinases (PTKs) play a key role in the regulation of cell proliferation, differentiation, metabolism, migration and survival. Due to their involvement in various forms of cancer, PTKs have become prominent targets for therapy. This new book gathers the latest research from around the globe in this dynamic field.

Table of Contents:

Serpin-Related Diseases (Aleksandra Topic—Institute of Medical Biochemistry, Faculty of Pharmacy, Belgrade, Serbia) pp.1-36

The Roles of Mammalian Mitogen-Activated Protein Kinase-Activating Protein Kinases (MAPKAPKs) in Cell Cycle Control
(Sergiy Kostenko, Alexey Shiryaev, Nancy Gerits, Ugo Moens - Univ. of Tromso, Faculty of Medicine, Institute of Medical Biology, Dept. of Microbiology and Virology, Tromso, Norway)pp.27-62

Rho-Kinase Inhibitor in Kidney Disease
(Toshio Nishikimi - Dept. of Hypertension and Cardiorenal Medicine, Dokkyo Medical Univ., Mibu, Japan pp.63-88

Targeting the Epidermal Growth Factor Receptor Pathway in Glioblastoma Multiforme and Other Intracranial Malignancies
(Marc-Eric Halatsch, Georg Karpel-Massler - Dept of Neurosurgery, Univ. of Heidelberg, Heidelberg, Germany)pp.89-106

The Serine Proteinase Inhibitor Z Alpha-1 Antitrypsin: Acting on the NF-kappaB System for Cytotoxicity (Matthew William Lawless, Department of Clinical Medicine, Trinity College, Dublin, St. James Hospital, Ireland)pp.107-124

Src Family Kinase Inhibitors in Cancer Therapy
(Faye M. Johnson, Gary E. Gallick - Dept. of Thoracic/Head and Neck Medical Oncology, The Univ. of Texas, Houston, TX, and others)pp.125-152

Protein Kinase Inhibitors in Cancer
(Yiguo Hu, Shaoguang Li - The Jackson Laboratory, Bar Harbor Maine)pp.153-166

Protein Kinase Inhibitors: New Research
Panagiotis Samaras, Frank Stenner - Department of Oncology, Univ. Hospital Zurich, Raemistrasse, Switzerland)pp.167-182

PAI-1 and the Diet-Induced Obesity Phenotype: Background Effects and Inbreeding (Bart M. De Taeye, Tatiana Novitskaya, and Douglas E. Vaughan, Department of Medicine, Division of Cardiovascular Medicine, Vanderbilt University, Nashville, TN)pp.183-198

The Structure of á1-Proteinase Inhibitor Polymer: Facts and Hypothesis
(Ewa Marszal—Division of Hematology, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland)pp.199-210

SERPINA5 Expression in the Male Reproductive Tract is altered with Advanced Age
(Matthew D Anway—Center For Reproductive Biology, Department of Biological Sciences, University of Idaho, Moscow, ID)pp.211-218

Vaspin: Visceral Adipose Tissue-Derived Serpin with Insulin-Sensitizing Effects (Jun Wada —Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Okayama, Japan)pp.219-228

Effect of Alpha2-antiplasmin on Tissue Remodeling
Yosuke Kanno and Hiroyuki Matsuno—Dept. of Clinical Pathological Biochemistry, Faculty of Pharmaceutical Science, Doshisha Women’s Collage of Liberal Arts, Kyoto, Japan)pp.229-236

Index pp.237-257

      Protein Biochemistry, Synthesis, Structure and Cellular Functions
   Binding: ebook
   Pub. Date: 2009 4th Quarter
   Pages: pp.257
   ISBN: 978-1-61209-350-5
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
Available Options:
Special Focus Titles
01.Violent Communication and Bullying in Early Childhood Education
02.Cultural Considerations in Intervention with Women and Children Exposed to Intimate Partner Violence
03.Chronic Disease and Disability: The Pediatric Lung
04.Fruit and Vegetable Consumption and Health: New Research
05.Fire and the Sword: Understanding the Impact and Challenge of Organized Islamism. Volume 2

Nova Science Publishers
© Copyright 2004 - 2022

Serpins and Protein Kinase Inhibitors: Novel Functions, Structural Features and Molecular Mechanisms