Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
            
  Top » Catalog » Books » My Account  |  Cart Contents  |  Checkout   
Quick Find
  
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
Brain, Body, Cognition - A continuation of Functional Neurology, Rehabilitation and Ergonomics
$325.00
Shopping Cart more
0 items
Information
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Notifications more
NotificationsNotify me of updates to Techniques in Epidermal Biology: An Integrated Approach to Autoimmune Skin Disease
Tell A Friend
 
Tell someone you know about this product.
Techniques in Epidermal Biology: An Integrated Approach to Autoimmune Skin Disease
Retail Price: $55.00
10% Online Discount
You Pay:

$49.50
Authors: Nicola Cirillo (University of Bristol, Bristol, UK) 
Book Description:
The high-throughput techniques underlying a systems level analysis of biological organisms have emerged as powerful tools in the study of disease mechanisms. On the other hand, they require substantial funding and multidisciplinary skills. Therefore, basic biochemical/cell biology methods from molecular bioscience are still needed to address key biological questions. This new book uses the autoimmune disease Pemphigus Vulgaris (PV) as an experimental model of epidermal disease. Simple molecular bioscience principles and high-throughput methods to clarify disease pathophysiology are presented, which lead to novel therapeutic modalities. (Imprint: Nova Biomedical Press)



We’ve partnered with Copyright Clearance Center to make it easy for you to request permissions to reuse Nova content.
For more information, click here or click the "Get Permission" button below to link directly to this book on Copyright Clearance Center's website.


Table of Contents:
Introduction

1. Pathophysiology of the Epidermis: Lesson from pemphigus, pp. 1-20

2. Patients, sera, and experimental models, pp. 21-35

3. Optimization of the experimental procedures: Semi-quantitative LCIF microscopy, C-HSU buffer, and KAD medium, pp. 37-47

4. Study of Anti-desmoglein autoimmunity: Pemphigus as a desmoglein-remodeling disease, pp. 49-76

5. Role on non-desmoglein and non-igg in pemphigus, pp. 77-94

6. Downstream signaling involved in acantholysis: I. Changes in cell cycle and protein phosphorylation, pp. 95-109

7. Downstream signaling involved in acantholysis: II. Secretion of proteinases and the “specific proteolysis, pp. 111-122
hypothesis” of pemphigus

8. Microarray analysis of diseased tissues: Cell adhesion is down-regulated on the gene level in pemphigus, pp. 123-138

9. Pharmacological block of acantholysis: Towards novel therapies for the treatment of pemphigus, pp. 139-151

Index

   Series:
      Immunology and Immune System Disorders
      Dermatology - Laboratory and Clinical Research
   Binding: Softcover
   Pub. Date: 2011 2nd quarter
   Pages: 6 x 9 (NBC - C)
   ISBN: 978-1-61209-621-6
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
Special Focus Titles
01.Violent Communication and Bullying in Early Childhood Education
02.Cultural Considerations in Intervention with Women and Children Exposed to Intimate Partner Violence
03.Chronic Disease and Disability: The Pediatric Lung
04.Fruit and Vegetable Consumption and Health: New Research
05.Fire and the Sword: Understanding the Impact and Challenge of Organized Islamism. Volume 2

Nova Science Publishers
© Copyright 2004 - 2020

Techniques in Epidermal Biology: An Integrated Approach to Autoimmune Skin Disease