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Amyloids: Composition, Functions and Pathology
Retail Price: $182.00
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$163.80
Editors: Irene P. Halcheck and Nancy R. Vernon
Book Description:
Assembly and deposition of physiologically generated, amyloidogenic proteins occur in various human diseases, referred to as amyloidoses, through misfolding that is either partial unfolding or partial folding of the proteins. A growing body of evidence suggests that misfolding of a given protein is driven by point mutations or by the presence of environmental factors favorable for amyloidogenesis. In this book, the authors present topical research in the study of the composition, function and pathology of amyloids, including the effect of yeast red pigment on amyloid fibrils in vivo and in vitro; amyloid precursor protein and its relation to Alzheimer's disease; amyloid precursor protein expression after traumatic brain injury; protein aggregation as a modulatory factor in EPMI and the atomic-resolution structures of prion AGAAAAGA amyloid fibrils. (Imprint: Nova Biomedical)

Please click on a chapter below to purchase separately

Chapter 1 - The Effect of Yeast Red Pigment on Amyloid Fibrils in Vivo and in Vitro (pp.1-32)
Authors / Editors: (O. V. Nevzglyadova, E. V. Mikhailova, A. V. Artemov, A. G. Mittenberg, I. M. Kuznetsova, K. K. Turoverov, M.A. Khodorkovskii, T. R. Soidla, Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russia, and others)

Chapter 2 - Amyloid Precursor Protein: Its Signaling Aspect and Alzheimer’s Disease (pp.33-60)
Authors / Editors: (Kohzo Nakayama, Hisashi Nagase, Chang-Sung Koh, Takeshi Ohkawara, Department of Anatomy, Department of Immunology and Infectious Diseases, Shinshu University, School of Medicine, Matsumoto, Nagano, Japan)
***Open Access Chapter. Free Download Available***

Chapter 3 - Study of Amyloid Precursor Protein Expression after Traumatic Brain Injury in the Rat (pp.61-82)
Authors / Editors: (Tatsuki Itoh, Motohiro Imano, Shozo Nishida, Masahiro Tsubaki, Shigeo Hashimoto, Akihiko Ito, Takao Satou, Department of Pathology, Kinki University Faculty of Medicine, Osaka, Japan, and others)

Chapter 4 - Mechanism of Neurotoxicity of Amyloid-Beta Peptide and the Protective Effects of Docosahexaenoic Acid (pp.83-102)
Authors / Editors: (Shahdat Hossain, Michio Hashimoto, Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka, Bangladesh, and others)

Chapter 5 - Protein Aggregation as a Modulatory Factor in EPM1 (pp.103-118)
Authors / Editors: (Mira Polajnar, Slavko Čeru, Nataša Kopitar Jerala, Dejan Caglič, Eva Žerovnik, Department of Biochemistry and Molecular and Structural Biology, Jožef Stefan Institute, Ljubljana, Slovenia, and others)
***Open Access Chapter. Free Download Available***

Chapter 6 - Molecular Dynamics Simulations of Amyloid  Peptides Containing D-Aspartic Acid Residues (pp.119-136)
Authors / Editors: (Akifumi Oda, Kana Kobayashi, Ohgi Takahashi, Faculty of Pharmaceutical Sciences, Tohoku Pharmaceutical University, Japan, and others)

Chapter 7 - Amyloid, Arises on the Membranes and Acts on the Membranes (pp.137-150)
Authors / Editors: (Katsuhiko Yanagisawa, National Center for Geriatrics and Gerontology, Morioka, Obu, Japan)

Chapter 8 - Insights into the Aggregation Pathway ofa-Synuclein (pp.151-164)
Authors / Editors: (Jillian Madine, Institute of Integrative Biology, University of Liverpool, Crown Street, Liverpool, United Kingdom)

Chapter 9 - A Critical Study of the Isosteres of 10th Cysteine Residue of Transthyretin Induced with Cysteine-S-Sulfonate by Ultra-High Resolution Mass Spectrometry (pp.165-176)
Authors / Editors: (Toyofumi Nakanishi, Noriyuki Iwasaki, Kazunori Saito, Shinnichi Wada, Masanori Yoshioka, Takashi Nirasawa, Takayuki Takubo, Department of Clinical and Laboratory Medicine, Osaka Medical College, Japan, and others)

Chapter 10 - Atomic-Resolution Structures of Prion AGAAAAGA Amyloid Fibrils (pp.177-186)
Authors / Editors: (Jiapu Zhang, School of Sciences, University of Ballarat, Mount Helen, Ballarat, Victoria, Australia)

Chapter 11 - Amyloidosis: Etiology, Pathogenesis and Diagnosis (pp.187-198)
Authors / Editors: (Laura Díez, Antonio G. Prado, Isabel G. Guijarro, Department of Otolaryngology, El Bierzo Hospital1, Spain)

Chapter 12 - Serum and Urine Free Light Chain Analysis in Evaluation of Amyloidosis AL and other Monoclonal Gammopathies (pp.197-216)
Authors / Editors: (Stanley S. Levinson, Laboratory Service, Department of Veterans Affairs Medical Center, Louisville, Kentucky, and others)

Chapter 13 - Transthyretin Val30Met Familial Amyloid Polyneuropathy in Japan (pp.217-232)
Authors / Editors: (Haruki Koike, Fumiaki Tanaka, Gen Sobue, Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan)

Chapter 14 - Amyloid Imaging and Biomarkers in MCI and Alzheimer’s Disease (pp.233-242)
Authors / Editors: (Katsutoshi Furukawa, Nobuyuki Okamura, Manabu Tashiro, Shozo Furumoto, Ren Iwata, Kazuhiro Yanai, Yukitsuka Kudo, Hiroyuki Arai, Department of Geriatrics and Gerontology, Division of Brain Sciences, Institute of Development, Aging and Cancer, Tohoku University, Japan)

   Series:
      Protein Biochemistry, Synthesis, Structure and Cellular Functions
      Protein Science and Engineering
   Binding: Hardcover
   Pub. Date: 2012-August
   Pages: 7 x 10 (NBC - R) 252pp.
   ISBN: 978-1-62100-538-4
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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