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Retinoic Acid: Structure, Mechanisms and Roles in Disease
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Editors: Li-Hong Cheng and Yuto Ito
Book Description:
Retinoic acid (RA) is a signaling molecule involved in many important pathways in every cell. When RA binds to RA receptors and activates them, cell cycle arrest, differentiation and apoptosis can occur. In this book, the authors present topical research in the study of the structure, mechanisms and roles in disease of retinoic acid. Topics discussed include retinoid signaling in mammalian inner ear development; nuclear receptors for retinoids involved in the control of expression activity of p-glycoprotein; retinoic acid signaling and immunotherapy of cancer; using retinoic acid in molecular medicine and retinol/vitamin A signaling and self-renewal of stem cells. (Imprint: Nova Biomedical)

Please click on a chapter below to purchase separately

Chapter 1 - Retinoid Signaling in Mammalian Inner Ear Development (pp.1-28)
Authors / Editors: (Dorothy A. Frenz, Mark K. Maconochie, Department of Cell Biology and Anatomy and Department of Otolaryngology, New York Medical College, Valhalla, New York, USA, and others)

Chapter 2 - Are Nuclear Receptors for Retinoids Involved in the Control of the Expression and Activity of P-Glycoprotein? (pp.29-52)
Authors / Editors: (Zdena Sulová, Julius Brtko, Dana Macejová, Albert Breier, Institute of Molecular Physiology and Genetics, Slovak Academy of Sciences, Vlárska, Bratislava, Slovakia, and others)
***Open Access Chapter. Free Download Available***

Chapter 3 - mRNA Diversity of Genes by Alternative Splicing during Neuronal Differentiation of NT2 Pluripotential Human Embryonal Carcinoma Cells by All-Trans Retinoic Acid (pp.53-86)
Authors / Editors: (Takao Isogai, Ai Wakamatsu, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyou-ku, Tokyo, Japan)
***Open Access Chapter. Free Download Available***

Chapter 4 - Retinoic Acid Signaling and Immunotherapy of Cancer (pp.87-104)
Authors / Editors: (Stefanie Kewitz, Julia Müller, Carolin Winkler, Martin S. Staege, Department of Pediatrics, Children’s Cancer Research Center. Martin-Luther-University Halle-Wittenberg, Halle, Germany)

Chapter 6 - Tretinoin-Cyclodextrin Complex in Skin Rejuvenation Therapy (pp.121-140)
Authors / Editors: (Keiko Takahash, Akiyoshi Takada, Department of Life Science and Sustainable Chemistry, Faculty of Engineering, The Center for Nanoscience and Technology, Tokyo Polytechnic University, Iiyama, Atsugi Kanagawa, Japan, and others)

Chapter 7 - Retinoic Acid: An Old Compound with a Potential for Future Use in Personalized Molecular Medicine (pp.141-156)
Authors / Editors: (Shi Ke, Wei Wang, Xiuchun Qiu, Fujun Zhang, Matthew L. Anderson, Claire Mach, Marina Konopleva, Jason T. Yustein, Chaoxia Zou, Xu Gao, Jie Lin, Jin Sun, Arlin G. Cameron, Department of Radiology, Baylor College of Medicine, Houston, Texas, USA, and others)

Chapter 8 - Retinol/Vitamin A Signaling and Self Renewal of Stem Cells (pp.157-164)
Authors / Editors: (Jaspal S. Khillan, Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA)

Chapter 9 - Retinoic Acid Regulates Sox2 Expression during Neuronal and Glial Differentiation in Mouse P19 Cells (pp.165-174)
Authors / Editors: (Roger Tremblay, Julie Haukenfrers, Joy Lei, Marianna Sikorska, Mahmud Bani-Yaghoub, Neurogenesis and Brain Repair Group, Institute for Biological Sciences, National Research Council Canada, Ottawa, ON, Canada, and others)

Chapter 10 - Alternatives to Reduce the Topical Retinoic Acid-Induced Skin Irritation (pp.175-192)
Authors / Editors: (G.A. Castro, L.A.M. Ferreira, Department of Pharmaceutics, Faculty of Pharmacy, Federal University of Minas Gerais, Brazil)

      Microbiology Research Advances
      Cell Biology Research Progress
   Binding: Hardcover
   Pub. Date: 2012 2nd Quarter
   Pages: 7x10 (NBC - R) 202pp.
   ISBN: 978-1-62100-597-1
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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Retinoic Acid: Structure, Mechanisms and Roles in Disease