Book Description:
Hemostasis (coagulation and fibrinolysis) is of importance in a broad range of medical disciplines. A high-quality hemostasis diagnosis enables a good therapy, which can be rather complicated without laboratory help. This yearbook gathers important contributions in this field and presents them in a coherent and logical format. (Imprint: Nova)

Table of Contents:
Preface

Thrombin Inhibitors Should Not Generate Thrombin!;pp. 1-2

The Development of Direct Thrombin and Factor XA Inhibitors;pp. 3-17
(F. Markwardt, Institute of Pharmacology, Erfurt, Germany)

Quantification of Lactate – Induced Thrombin Generation;pp. 19-26
(Thomas W. Stief, University Hospital, Marburg, Germany)

Quantification of Cholesterol – Induced Thrombin Generation;pp. 27-35
(Thomas W. Stief,University Hospital, Giessen & Marburg, Germany)

Quantification of Triglycerides – Induced Thrombin Generation;pp. 37-45
(Thomas W. Stief, University Hospital, Giessen & Marburg, Germany)

Thrombin Generation by Phenytoin;pp. 47-55
(Thomas W. Stief, University Hospital, Giessen & Marburg, Germany)

Citrate Triggers Thrombin Generation;pp. 57-61
(Thomas W. Stief, University Hospital, Giessen & Marburg, Germany)

Thrombin Generation Triggered by Ultra-Low-Concentrations of Heparins;pp. 63-74
(Thomas W. Stief,University Hospital, Giessen & Marburg, Germany)

The Reactivity of Endotoxin Depends on the Protein Concentration of the Sample;pp. 75-78
(Thomas W. Stief, University Hospital, Marburg, Germany)

First Specific Functional Chromogenic Plasma-Tests for Thrombin (Generation);pp.79-84
(Thomas W. Stief, University Hospital, Giessen & Marburg, Germany)

Activation of Coagulation by a Simple Ultrasound Flow Model;pp. 85-100
(EM Müller-Stüler, Thomas W. Stief and V. Klingmüller, Dept. of Pediatric Radiology, University Hospital, Marburg, Germany)

Thrombin Generation by Valproate;pp. 101-144
(Thomas W. Stief and Morad Mohrez, Dept. of Clinical Chemistry, University Hospital, Giessen & Marburg, Germany)

Cations Modulate Thrombin Generation;pp. 145-164
(Thomas W. Stief, University Hospital, Giessen & Marburg, Germany)

Thrombin Generation by Paracetamol;pp. 165-174
(Thomas W. Stief, University Hospital, Giessen & Marburg, Germany)

Thrombin Generation by Levetiracetam;pp. 175-183
(Thomas W. Stief, University Hospital, Giessen & Marburg, Germany)

Quantification of Thrombin Generation by Vancomycin;pp. 185-192
(Thomas W. Stief, University Hospital, Giessen & Marburg, Germany)

Thrombin Generation by Creatinine;pp. 193-202
(Thomas W. Stief, University Hospital, Marburg, Germany)

Thrombin Generation Must be Corrected for Supplemented Matrix;pp. 203-206
(Thomas W. Stief,University Hospital, Giessen & Marburg, Germany)

Thrombin Generation by Fosfomycin;pp. 207-210
(Thomas W. Stief, University Hospital, Giessen & Marburg, Germany)

Fosfomycin and Fibrinolysis;pp. 211-218
(Thomas W. Stief, University Hospital, Giessen & Marburg, Germany)

Lysis of Fibrin-Micro-Clots by Urokinase/Plasminogen;pp. 219-238 (Thomas W. Stief, University Hospital, Marburg, Germany)

Singlet Oxygen and Thrombin Generation in RECA;pp. 239-255
(Thomas W. Stief, University Hospital, Giessen & Marburg, Germany)

Addition Calibration of LPS Reactivity in Normal Plasma;pp. 257-263
(Thomas W. Stief, University Hospital, Marburg, Germany)

Index