Book Description:
Hemostasis (coagulation and fibrinolysis) is of importance in a broad range of medical disciplines. A high-quality hemostasis diagnosis enables a good therapy, which can be rather complicated without laboratory help. This yearbook gathers important contributions in this field and presents them in a coherent and logical format. (Imprint: Nova)

Table of Contents:
Preface

The Researcher´s Publication Index;pp. 1-3
(Thomas W. Stief, University Hospital Giessen and Marburg,Germany)

Diagnosis of Normal or Pathologic Systemic Thrombin Generation;pp. 5-6
(Thomas W. Stief,University Hospital,Marburg,Germany)

Singlet Oxygen: A New Weapon Against Viruses;pp. 7-8
(Thomas W. Stief, Universitty Hospital,Marburg, Germany)

Early diagnosis of Severe Sepsis by Gram-Negative Bacteria or Fungi;pp. 9-10
(Thomas W. Stief,University Hospital,Marburg, Germany)

Frustratingly Activated Fibrinolysis in Severe Sepsi;pp. 11
(Thomas W. Stief,University Hospital,Marburg,Germany)

Improvement of Cellular Fibrinolysis;pp. 13
(Thomas W. Stief,University Hospital,Marburg,Germany)

Coagulation Activation by Volume Replacement;pp. 15-16
(Thomas W. Stief,University Hospital,Marburg,Germany)

20 % EXCA (0.1 IU/ml Thrombin) the Ideal Anticoagulant Target Value;pp. 17-20
(Thomas W. Stief,University Hospital Giessen and Marburg,Germany)

Thrombin Generation by the Drug Gentamicin;pp. 21-60
(Thomas W. Stief and Dada Aishe Albert,University Hospital of Marburg,Germany)

Thrombin Generation by Tryptophan;pp. 61-68
(Morad Mohrez and Thomas W. Stief,University Hospital Giessen and Marburg,Germany)

Thrombin Generation by an Actual Lot of Asparaginase;pp. 69-74
(Thomas W. Stief, Danuta Chalkit and Angela Korb-Bangang,Dept. of Clinical Chemistry University,Hospital Giessen and Marburg,Germany)

Thrombin Generation by Diagnostic Ultrasound;pp. 75-101
(Thomas W. Stief, Volker Klingmüller and Eva Müller-Stüler,University Hospital Marburg,Germany and others)

Bleeding Therapy by Coagulation Proteases or Contact Triggers;pp. 103-104
(Thomas W. Stief, Institute of Laboratory Medicine and Pathobiochemistry,University Hospital,Marburg,Germany)

Asparaginase and Thrombin Generation;pp. 105-106
(Thomas W. Stief,University Hosital,Marburg,Germany)

Diagnosis of Activation of the Contact Phase of Coagulation;pp. 107-108
(Thomas W. StiefInstitute of Laboratory Medicine and Pathobiochemistry,University Hospital,Marburg,Germany)

A Now Measurable Important Side Effect of Drugs: Enhanced Thrombin Generation;pp. 109-110
(Thomas W. Stief,University Hospital,Marburg,Germany)

Synthetic Inhibitors of Thrombin or of Factor 10a May Enhance Intrinsic Thrombin Generation;pp. 111-112
(Thomas W. Stief.University Hospital,Marburg, Germany)

Cytostatics and Thrombin Generation;pp. 113-114
(Thomas W. Stief, University Hospital,Marburg,Germany)

Immunosuppressors Can Generate Thrombin;pp. 115-116
(Thomas W. Stief,University Hospital,Marburg,Germany)

Antibiotics Can Generate Thrombin;pp. 117-118
(Thomas W. Stief,University Hospital,Marburg,Germany)

Factor 12 Activation in Two Purified Systems;pp. 119-140
(Thomas W. Stief,University Hospital Giessen and Marburg,Germany)

Zn2+, Hexane, or Glucose Activate Factor 12 and/or Prekallikrein in Two Purified Systems;pp. 141-157
(Thomas W. Stief,University Hospital Giessen and Marburg,Germany)

Systemic Thrombin Generation by Valproate;pp. 159-169
(M. Mohrez, M. Alrifai and T. W. Stief,University Hospital Giessen and Marburg,Germany)

Cations Modulate Extrinsic Thrombin Generation;pp. 171-179
(Thomas W. Stief,University Hospital Giessen and Marburg,Germany)

Polyphosphates Modulate Thrombin Generation;pp. 181-186
(Thomas W. Stief,UYniversity Hospital Giessen and Marburg,Germany)

Low-Molecular-Weight-Heparin (LMWH) Corrects Insufficient Plasmatic Antithrombin Activity;pp. 187-197
(Thomas W. Stief, University Hospital Giessen and Marburg,Germany)

Thrombin Generation by Therapeutic Fibrinogen;pp. 199-214
(Thomas W. Stief,University Hospital Giessen and Marburg,Germany)

Index