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Structural Biology of Antiapoptotic Proteins of BCL-2 Family $195.00
Authors: Valery G. Veresov (Department of Cell Biophysics, Institute of Biophysics and Cell Engineering, Minsk, Belarus) 
Book Description:
The BCL-2 family proteins are crucial regulators of the apoptotic process. This book covers recent structure-based insights into the mechanisms of action of antiapoptotic BCL-2 family proteins as well as into the interactions between antiapoptotic proteins and their ligands. While the main focus is on the apoptotic processes in mammals, the great part of the book is devoted to viral homologues of Bcl-2 family antiapoptotic proteins. (Imprint: Nova Biomedical)

Table of Contents:
Preface

1. Introduction

2. Proteins of BCL-2 Family

3. Extrinsic and Intrinsic Pathways of Programmed Cell Death

4. Models of Apoptosis

5. Antiapoptotic Proteins. Basic Properties and Functions

6. Gene Products and Tissue Specificity of Expression of Antiapoptotic Proteins

7. Structures of Antiapoptotic Proteins in Solution

8. 3-D Structures of Viral Antiapoptotic Proteins in Solution

9. What Can We Know and What Can We Anticipate About the Structures of Antiapoptotic Proteins at Membranes

10. Regulation of Antiapoptotic Proteins

11. The Endoplasmic Reticulum in Apoptosis and Antiapoptosis

12. The Antiapoptotic Action of Antiapoptotic Proteins

13. Physiological Role of Antiapoptotic Proteins

14. Carcinogenesis, Aberrant Apoptosis and the Proteins of BCL-2 Family

15. Therapeutic Strategies Against Antiapoptosis for Cancer Treatment

Conclusion

References

   Series:
      Protein Biochemistry, Synthesis, Structure and Cellular Functions
   Binding: ebook
   Pub. Date: 2012
   Pages: 7 x 10 (NBC - C)
   ISBN: 978-1-61942-395-4
   Status: AN
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Structural Biology of Antiapoptotic Proteins of BCL-2 Family