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Amyotrophic Lateral Sclerosis: Symptoms, Treatment and Prognosis
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$188.10
Editors: Katashi Segawa and Ryota Ijichi
Book Description:
Amyotrophic Lateral Sclerosis (ALS) or Lou Gehrig's disease is an adult-onset fatal neurodegenerative disease characterized by progressive apoptosis of upper and lower motor neurons in the brain, brainstem and spinal cord. This results in paralysis of bulbar, limb, thoracic and abdominal skeletal muscles, and death within 2-5 years of diagnosis. In this book, the authors present current research on the symptoms, treatment and prognosis of ALS. Topics include audiological profiles and hearing loss in ALS patients; the role of the lipid transcription factor and sterol regulatory element binding protein 1 (SREBP1) in ALS; molecular targeted therapy for ALS; physical and communication disabilities in ALS; psychological interventions for ALS patients and their caregivers; and a study of ALS progression and propagation. (Imprint: Nova Biomedical)

Table of Contents:
Preface pp. i-x

The Audiological Profile and Perceptions of Hearing Loss in Individuals with Amyotrophic Lateral Sclerosis
(Elena Philippou, Karin Joubert, University of the Witwatersrand, Johannesburg, South Africa)pp. 1-56

Role of Lipid Transcription Factor, Sterol Regulatory Element Binding Protein 1 (SREBP1) in ALS: Potential Therapeutic Interventions
(Siavash Khalaj, Changiz Taghibiglou, Department of Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, Canada)pp. 57-84

Molecular Targeted Therapy against Amyotrophic Lateral Sclerosis
(Makoto Urushitani, Toshifumi Morimura, Shiga University of Medical Science, Molecular Neuroscience Research Center, Seta-Tsukinowa-cho, Otsu, Shiga, Japan)pp. 85-108

Amyotrophic Lateral Sclerosis: Exploring the Impact of Decreased Speech Intelligibility on Marital Communication
(Karin Joubert, University of the Witwatersrand, Johannesburg, South Africa)pp. 109-126

Psychological Interventions in Amyotrophic Lateral Sclerosis
(Francesco Pagnini, Department of Psychology, Catholic University of Milan, Italy, and others)pp. 127-138

Amyotrophic Lateral Sclerosis and Lipid Peroxidation
(Moses Henderson,Seth Van Zant, Tanea T. Reed, Department of Chemistry, Eastern Kentucky University, Richmond, Kentucky, USA)pp. 139-150

The Spread Pattern and Survival in Sporadic ALS: “How Does ALS Progress or Propagate?”
(Fumiharu Kimura, Division of Neurology, The First Department of Internal Medicine, Osaka Medical College, Daigaku-machi, Takatsukishi, Osaka, Japan)pp. 151-164

Index pp. 165-176

   Series:
      Neurodegenerative Diseases - Laboratory and Clinical Research
      Neuroscience Research Progress
   Binding: Hardcover
   Pub. Date: 2013- January
   Pages: 186, 7 x 10 (NBC - R)
   ISBN: 978-1-62257-679-1
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Amyotrophic Lateral Sclerosis: Symptoms, Treatment and Prognosis