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Animal Models in Cancer Research and Human Disease: Applications, Outcomes and Controversies
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Editors: Sean A. Murray
Book Description:
This book discusses the applications, outcomes and controversies of using animal models in cancer research and human disease. Topics include murine models of sporadic and inflammation-related colon carcinogenesis with particular focus on the AOM/DSS chemically induced colorectal cancer model; large animal models of human cardiovascular disease; developments of cell therapeutic strategies for Alzheimer's disease using animal models; the techniques and limitations of murine models of human colorectal cancer; animal models for antineoplastic chemotherapy-induced alopecia; and development of columnar-lined esophagus with or without goblet cells in rate duodengastroesophageal reflux models through gut regenerative cell lineage (GRCL). (Imprint: Nova Biomedical)

Please click on a chapter below to purchase separately

Chapter 1 - Murine Models of Sporadic and Inflammation-Related Colon Carcinogenesis with Particular Focus on the AOM/DSS Chemically Induced Colorectal Cancer Model (pp. 1-46)
Authors / Editors: (M. De Robertis, V.M. Fazio, E. Signori, Laboratory of Molecular Medicine and Biotechnology, CIR, University Campus Bio-Medico of Rome, Rome, Italy, and others)

Chapter 2 - Large Animal Models of Human Cardiovascular Disease (pp. 47-68)
Authors / Editors: (Naritatsu Saito, Fumiaki Ikeno, Cardiovascular Medicine, Kyoto University¤ Kyoto, Japan, and others)

Chapter 3 - Canine Breast Cancer and Lymphoma as Models in Cancer Research (pp. 69-86)
Authors / Editors: (Farruk Mohammad Lutful Kabir, Ann Marie OfNeill, Bruce F. Smith, Richard Curtis Bird, Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, and others)

Chapter 4 - Development of Cell Therapeutic Strategies for Alzheimerfs Disease Using Animal Models (pp. 87-104)
Authors / Editors: (Kazuyuki Takata, Shohei Kawanishi, Yumiko Touji, Tetsuya Takada, Yoshihisa Kitamura, Eishi Ashihara, Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto, Japan)

Chapter 5 - Animal Models for Antineoplastic Chemotherapy-Induced Alopecia (pp. 105-120)
Authors / Editors: (Tongyu C. Wikramanayake, Sonal Choudhary, Lucia M. Mauro, Joaquin J. Jimenez, Department of Dermatology and Cutaneous Surgery, and Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL, USA)

Chapter 6 - Murine Models of Human Colorectal Cancer: Techniques and Limitations (pp. 121-132)
Authors / Editors: (Jasneet Singh Bhullar, Vijay K. Mittal, Department of Surgery, Providence Hospital & Medical Centers, Southfield, MI, USA)

Chapter 7 - Development of Columnar-Lined Esophagus With or Without Goblet Cells in Rat Duodenogastroesophageal Reflux Models through Gut Regenerative Cell Lineage (GRCL) (pp. 133-142)
Authors / Editors: (Ken-ichi Mukaisho, Takanori Hattori, Department of Pathology, Shiga University of Medical Science, Seta Tukinowa-cho, Otsu, Shiga, Japan)
***Open Access Chapter. Free Download Available***

      Microbiology Research Advances
      Animal Science, Issues and Professions
   Binding: Hardcover
   Pub. Date: 2013- March
   Pages: 162, 7x10 - (NBC-R)
   ISBN: 978-1-62417-587-9
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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Animal Models in Cancer Research and Human Disease: Applications, Outcomes and Controversies