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Tumor Necrosis Factor: Structure, Enzyme Regulation and Role in Health and Disease
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Editors: Agueda Escarra
Book Description:
Tumor necrosis factor-alpha (TNF-a) is a potent pro-inflammatory cytokine exerting pleiotropic effects on various cell types and plays a critical role in the pathogenesis of chronic inflammatory diseases. In this book, the authors discuss the structure, enzyme regulation and role in health and disease of TNF. Topics include TNF-a related to signal pathways and neuronal diseases; the role of TNF-a in rheumatoid arthritis and autoimmunity; the presence of 308-A TNF allele and its association with the clinical parameters of myelodysplastic syndromes; the significance of TNF in the immune response against tuberculosis; and TNF-a signaling and cathespin B. (Imprint: Novinka)

Please click on a chapter below to purchase separately

Chapter 1 - Tumor Necrosis Factor-Alpha Related Signal Pathways and Neuronal Diseases(pp. 1-28)
Authors / Editors: (Yuki Murakami, Yukio Imamura, Satoko Mitani, Masato Hoshi, Yuko Arioka, Yasuko Yamamoto, Akitoshi Seiyama, Kuniaki Saito, Human Health Sciences, Graduate School of Medicine and Faculty of Medicine, Kyoto University, Kyoto, Japan, and others)
***Open Access Chapter. Free Download Available***

Chapter 2 - Role of TNF-¦Á in Rheumatoid Arthritis (pp. 29-52)
Authors / Editors: (Guangjie Chen, Jian Hong, Department of Immunology, Shanghai JiaoTong University School of Medicine, Shanghai Institute of Immunology, Shanghai, China, and others)

Chapter 3 - The Role of Tumor Necrosis Factor Alpha in Autoimmunity (pp. 53-74)
Authors / Editors: (Mariana Postal, Simone Appenzeller, Department of Medicine, Rheumatology Unit, Faculty of Medical Science, State University of Campinas, Brazil)

Chapter 4 - The Presence of -308A TNF Allele is Associated with Clinical Parameters of Myelodysplastic Syndromes (pp. 75-92)
Authors / Editors: (Yesica Bestach, Mar¨ªa G. Flores, Francisco Sakamoto, Raquel Bengi¨®, Irene Larripa, Carolina B. Belli, Laboratorio de Gen¨¦tica Hematol¨®gica, Instituto de Medicina Experimental (IMEX-CONICET)/ Academia Nacional de Medicina (ANM), Buenos Aires, Argentina, and others)

Chapter 5 - Significance of TNF in the Immune Response against Tuberculosis (pp. 93-112)
Authors / Editors: (Guadalupe Garc¨ªa-Elorriaga, Guillermo del Rey-Pineda, Hospital de Infectolog¨ªa, Centro M¨¦dico Nacional La Raza (CMNR), Instituto Mexicano del Seguro Social (IMSS), M¨¦xico, and others)

Chapter 6 - TNF-¦Á Signaling and Cathespin B (pp. 113-128)
Authors / Editors: (Zhou Wu, Hiroshi Nakanishi, Department of Aging Science and Pharmacology, Faculty of Dental Sciences, Kyushu University, Fukuoka, Japan, and others)

      Cell Biology Research Progress
   Binding: Softcover
   Pub. Date: 2013
   Pages: 151, 6x9 - (NBC-R)
   ISBN: 978-1-62417-721-7
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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Tumor Necrosis Factor: Structure, Enzyme Regulation and Role in Health and Disease