Book Description:
Memory impairment due to aging and various memory disorders represent a great medical challenge to our society. Since the publication of the fifth volume of this collection, the rapid progress in the research fields of Alzheimer’s disease (AD) and other types of dementias continues through the intense efforts of research scientists worldwide. This sixth volume contains eight chapters, bringing together a presentation of scientific frontiers in current AD/dementia research. The topics include a discussion on impairments in dementias, memory binding in AD, therapeutic targeting of BACE1 and neprilysin, Tau Immunotherapy, targeting 5-lipoxygenase targets for tauopathy, potential therapeutics for frontotemporal dementia, potential therapeutics for Down’s syndrome, and cognitive rehabilitation in multiple sclerosis. Research advances in these areas are presented and discussed in great detail in the chapters. The book will be highly valuable to students and scientists worldwide who are interested in the scientific research and progress in AD and memory disorders. (Imprint: Nova Biomedical)

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Table of Contents:
Preface

Chapter 1 pp. 1-26. "Loss of the Future": Prospection Impairments in the Dementias
(Muireann Irish, School of Psychology, the University of New South Wales, Australia, and others)

Chapter 2 pp. 27-58. Memory Binding in Alzheimer’s Disease
(Mario Alfredo Parra, Psychology, Heriot-Watt University, UK, and others)

Chapter 3 pp. 59-98. Alzheimer’s Disease Therapy Targeting BACE1 and Neprilysin
(Masuo Ohno, Center for Dementia Research, Nathan Kline Institute, Orangeburg, New York, USA, and others)

Chapter 4 pp. 99-114. Advances in Tau Immunotherapy
(Julia Gerson and Rakez Kayed, Mitchell Center for Neurodegenerative Diseases, University of Texas Medical Branch, Galveston, TX, USA, and others)

Chapter 5 pp. 115-128. The 5-Lipoxygenase as a Therapeutic Target for Tauopathy
(Domenico Praticò, Department of Pharmacology, Center for Translational Medicine, Temple University, Philadelphia, PA, USA)

Chapter 6 pp. 129-168. Frontotemporal Dementia and Potential Therapeutics
(Fiona Kumfor, Sandra Baez and Agustin Ibanez, Neuroscience Research Australia, Barker Street, Randwick, Sydney, Australia, and others)

Chapter 7 pp. 169-194. Neurodegeneration and Memory Loss in Down Syndrome: Perspectives on Potential Therapeutics
(Aurélie Ledreux, Eric Hamlett, Jason Lockrow, Krishna Bharani, and Ann-Charlotte Granholm, Department of Neuroscience and the Center on Aging, Medical University of South Carolina, Charleston, SC, USA, and others)

Chapter 8 pp. 195-234. Cognitive Rehabilitation in Multiple Sclerosis
(Joshua Sandry, Nadine Akbar, Mark Zuppichini, and John DeLuca, Psychology Department, Montclair State University, Montclair, NJ, USA, and others)

Contributors

Index