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Stem Cells and Cartilage Tissue Engineering Approaches to Orthopaedic Surgery
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Authors: Wasim S Khan (University College London Institute of Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore, London) Timothy E Hardingham (UK Centre for Tissue Engineering and Wellcome Trust Centre for Cell Matrix Resear 
Book Description:
Tissue is frequently damaged or lost in injury and disease. There has been an increasing interest in stem cell applications and tissue engineering approaches in surgical practice to deal with damaged or lost tissue. Tissue engineering is an exciting strategy being explored to deal with damaged or lost tissue. It is the science of generating tissue using molecular and cellular techniques, combined with material engineering principles, to replace tissue. This could be in the form of cells with or without matrices. Although there have been developments in almost all surgical disciplines, the greatest advances are being made in orthopaedics, especially in cartilage repair. This is due to many factors including the familiarity with bone marrow derived mesenchymal stem cells and cartilage being a relatively simpler tissue to engineer. Unfortunately significant hurdles remain to be overcome in many areas before tissue engineering becomes more routinely used in clinical practice.

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Table of Contents:

Chapter 1. Stem Cells, pp. 1-3

Chapter 2. Sources of Adult Mesenchymal Stem Cells, pp. 5-8

Chapter 3. Differentiation of Stem Cells, pp. 9-12

Chapter 4. Stem Cell Markers, pp. 13-19

Chapter 5. Articular Cartilage, pp. 21-24

Chapter 6. Current Surgical Treatment Modalities, pp. 25-27

Chapter 7. Tissue Engineering Approaches for Articular Cartilage Defects, pp. 29-31


      Surgery - Procedures, Complications, and Results
   Binding: Softcover
   Pub. Date: 2010
   Pages: 6 x 9
   ISBN: 978-1-60876-864-6
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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Stem Cells and Cartilage Tissue Engineering Approaches to Orthopaedic Surgery