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Significance of Free Radical-Modified Fibrinogen in Thrombosis and Related Diseases $59.00
Authors: Boguslaw Lipinski (Harvard Medical School, Boston, MA, USA) 
Book Description:
Conversion of a soluble fibrinogen into insoluble fibrin with thrombin leads to the formation of a hemostatic plug that under physiological conditions is degraded by plasmin. Thrombosis is considered to be a result of an imbalance between procoagulant and anticoagulant activities of blood and the persistent presence of fibrin clots in the coronary, pulmonary or cerebral circulations. The main component of a thrombus is fibrin formed from fibrinogen by the action of thrombin. Human plasma fibrinogen is one of the largest plasma proteins composed of three pairs of polypeptide chains linked together by means of disulfide bonds. This new book discusses and presents information regarding the significance of free radical-modified fibrinogen in thrombosis and related diseases.

Imprint: Nova Biomedical

Table of Contents:
1. Introduction

2. Properties and Functions of Fibrinogen

3. Fibrin and Fibrinolysis

4. Oxidative Stress versus Free Radical Stress

5. Hydroxyl Radical-Induced Modification of Human Fibrinogen

6. Hydroxyl Radical-Modified Fibrinogen in Various Pathologic Conditions

7. Conclusion

Index

   Series:
      Cardiology Research and Clinical Developments
   Binding: ebook
   Pub. Date: 2011
   Pages: 6 x 9
   ISBN: 978-1-61728-643-8
   Status: AV
  
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Significance of Free Radical-Modified Fibrinogen in Thrombosis and Related Diseases