Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
  Top » Catalog » Books » Engineering » Mechanical Engineering » Computational Fluid Dynamics: Theory, Analysis and Applications Chapters » My Account  |  Cart Contents  |  Checkout   
Quick Find
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
Doxycycline: Medical Uses and Effects
Shopping Cart more
0 items
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Notifications more
NotificationsNotify me of updates to Computational Modelling in Tissue Engineering: Providing Light in Times of Darkness pp. 243-266
Tell A Friend
Tell someone you know about this product.
Computational Modelling in Tissue Engineering: Providing Light in Times of Darkness pp. 243-266 $0.00
Authors:  (Ryan J. McCoy, Daniel J. Kelly, Fergal J. O’Brien, Department of Anatomy, Royal College of Surgeons in Ireland, Dublin 2, Ireland, and others)
The human body can be considered an extremely complex machine. The demands placed on this machine over the lifetime of an individual or their natural genetic predisposition to particular conditions can result in the failure of native internal structures; for example, hips, knees, hearts or kidneys. Computational modelling has played a key role in the realisation of mechanically engineered replacements that can either be implanted internally (e.g ventricular assist devices and orthopaedic implants) or used to replace organ functionality externally (e.g kidney dialysis machines). This has enabled temporary ablation of the body‘s decline in some instances, but the provision of a biologically and anatomically relevant substitute capable of integrating into the host and continuing the original function unaided for the remaining lifetime of the individual, has yet to reach fruition. Interdisciplinary collaboration over the last 40 years between the engineering and scientific communities, has pursued and continues to pursue, the development of physiologically representative substitutes through the cultivation of tissue ex-vivo or through the induction of tissue growth in-vivo (tissue engineering and regenerative medicine). The intrinsic complexity of these biological systems means that experimentally prizing apart the individual mechanisms at play may not always be viable. Computational modelling tools thus have the potential to prove a very powerful addition once again; providing light where there is darkness in this emerging field and promoting furthered understanding. 

Available Options:

  Open Access item.
  Click below PDF icon for free download.


This is an Open Access item. Click above PDF icon for free download.
Special Focus Titles
01.Violent Communication and Bullying in Early Childhood Education
02.Cultural Considerations in Intervention with Women and Children Exposed to Intimate Partner Violence
03.Chronic Disease and Disability: The Pediatric Lung
04.Fruit and Vegetable Consumption and Health: New Research
05.Fire and the Sword: Understanding the Impact and Challenge of Organized Islamism. Volume 2

Nova Science Publishers
© Copyright 2004 - 2021

Computational Modelling in Tissue Engineering: Providing Light in Times of Darkness pp. 243-266