Book Description:
Nephrology deals with the study of the function and diseases of the kidney. Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the cause of renal failure in 5-10% of the patients in dialysis or transplantation. This book discusses the several conditions which are associated with the rate of progression. Peritoneal dialysis (PD), which has been widely used as one of the major renal replacement therapies for end-stage renal disease (ESRD) patients is also explored in this book. Furthermore, the important role of PAI-1 and the value of therapeutic approaches targeting PAI-1 in progressive renal fibrosis is also examined. Because renal interstitial fibrosis occurs in virtually all the progressive renal diseases leading to end-stage renal failure, controlling it would be a reasonable therapeutic strategy. Other chapters in this book include a review of therapeutic plasma exchanges (TPE), the potential mechanisms that may regulate the effect of macrophages upon renal interstitial fibrosis and the pathophysiological implications of inflammation in the pathogenesis of diabetic nephropathy.

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Table of Contents:
Preface

New Pathogenic Perspectives in Diabetic Renal Disease: Diabetic Nephropathy as an Inflammatory Condition;pp. 1-32
(Juan F. Navarro-González, Carmen Mora-Fernández, Mercedes Muros, Javier García, Nephrology Service and Research Unit, University Hospital Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain, and others)

Indexing Glomerular Filtration Rate for Body Surface Area: Myth and Reality;pp. 33-53
(Pierre Delanaye, Christophe Mariat, Etienne Cavalier, Jean-Marie Krzesinski, University of Liège, Department of Nephrology, Dialysis, Hypertension, Transplantation, CHU Sart Tilman, Liège, Belgium and others)

Advances in the Peritoneal Dialysis and Future Prospects;pp. 55-73
(Kook-Hwan Oh, M.D., Ph.D., Curie Ahn, M.D., PhD., Renal Division, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea)

Role of Plasminogen Activator Inhibitor-1 in the Development of Renal Interstitial Fibrosis;pp. 75-90
(Takashi Oda, MD, Department of Nephrology, National Defense Medical College, Saitama, Japan)

Pathogenesis and Resolution Mechanisms of Acute Poststreptococcal Glomerulonephritis;pp. 91-107
(Takashi Oda, MD., and Nobuyuki Yoshizawa, Department of Nephrology, National Defense Medical College, Saitama, Hemodialysis Unit, Chofu Hospital, Tokyo, Japan)

Progression of Autossomal Dominant Polycystic Kidney Disease: A Follow-up Study of a Large Cohort in a Single Center;pp.109-123
(Edgar A. F. de Almeida, MD, José António Lopes, MD, M. Martins Prata, MD, PhD., A. Gomes da Costa , MD, Serviço de Nefrologia e Transplantação Renal, Centro Hospitalar Lisboa Norte, EPE, Lisboa, Portugal)

Genetics in Clinical Nephrology;pp. 125-138
(Hansjorg Rothe, Kuratorium fur Dialyse und Nierentransplantation, Dept. of Nephrology and Hypertension, Klinikum Newmarkt, Germany)

Plasma Exchanges Prescription for Nephrologists;pp. 139-151
(Seck Sidy Mohamed (MD), Diouf Boucar (MD), Nephrology Department, Teaching Hospital Aristide Le Dantec, France

The Role of Macrophages in Obstructive Nephropathy;pp. 153-161
(Masashi Nishida, MD, PhD., and Kenji Hamaoka, Department of Pediatric Cardiology and Nephrology, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kyoto (Japan)

Whence Forth After the GWAS Wave for Diabetic Nephropathy?;pp. 163-171
(Daniel P.K. Ng, PhD, Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore)

Index