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01.Inflammatory Conditions of the Colon
02.Handbook of Pharyngeal Diseases: Etiology, Diagnosis and Treatment
03.Effects, Diagnosis and Management of Extra-Esophageal Reflux
04.Tumor Budding in Colorectal Cancer: Recent Progress in Colorectal Cancer Research (Horizons in Cancer Research, Volume 8)
05.Crohn's Disease: Etiology, Pathogenesis and Interventions
06.Irritable Bowel Syndrome
07.Focus on Colorectal Cancer Research (Horizons in Cancer Research, Volume 4)
08.Pancreatic Cancer: New Research
09.Sleep Effect on Gastrointestinal Health and Disease: Translational Opportunities for Promoting Health and Optimizing Disease Management
10.Therapeutic Perspectives of Gastrointestinal Melatonin (pp. 233-252)
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Effects, Diagnosis and Management of Extra-Esophageal Reflux
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Editors: Nikki Johnston, Robert J. Toohill (Medical College of Wisconsin, Milwaukee, WI)
Book Description:
Over the past twenty plus years clinicians have noted significant disorders of the lung, larynx, pharynx, nose, sinuses and middle ear that occur because of duo-denogastric refluxate (DGR) extending to these areas. While it has long been evident that gastric contents reaches the esophagus and will cause problems in the form of gastroesophageal reflux disease (GERD) the disorders of extra-esophageal reflux (EER) are increasingly causing morbidity to patients. Recently there have been basic and clinical studies indicating that other components of DGR cause damage to extra-esophageal structures. The combination of state of the art research and clinical presentations of EER make this book very valuable to those who investigate and manage patients.

Table of Contents:

1. History of Extra-Esophageal Reflux;pp. 1-10
(Robert J. Toohill, The Medical College of Wisconsin, Milwaukee)

2. Epidemiology of Extra-Esophageal Reflux Disease;pp. 11-18
(Rukiye Vardar, and Serhat Bor, Ege University School of Medicine, Ismir, Turkey)

3. Acid;pp. 19-27
(Serhat Bor,Ege University School of Medicine, Ismir,Turkey)

4. Pepsins;pp. 29-41
(Jeffrey P. Pearson, Shruti Parikh, Andrew G. N. Robertson, Rachel Stovold) and Iain A. Brownlee, Institutes for Cell and Molecular Biosciences and Cellular Medicine, New Castle University, UK)

5. Bile and Bilitec;pp. 43-50
(Natalya Chernichenko, MD; Jagdeep Hundal, MD and Clarence T. Sasaki, Yale University School of Medicine, New Haven, Ct, Supported in part by the Virginia Alden Wright Fund)

6. PH Monitoring;pp. 51-64
(Justin S. Golub and Michael M. Johns III, University of Washington, Seattle,WA,USA and others)

7. Impedance-pH Reflux Monitoring;pp. 65-78
(Jerry E. Mabary and Donald O. Castell,Sandhill Scientific, Highlands Ranch, CO,USA and others)

8. Use of Impedance pH Monitoring for Detection and Diagnosis of Extra-Esophageal Reflux;pp. 79-88
(Renato Soares and Brant K. Oelschlager, University of Washington,Seattle,USA)

9. The Role of the Esophagography in the Evaluation of Reflux Disease;pp. 89-96
(Peter C. Belafsky and Catherine J. Rees, University of California, Davis, Sacramento, CA and others)

10. TRans-Nasal Esophagoscopy (TNE);pp. 97-114
(Ingo. F. Hermann, Sara A. Recio, F.Cirillo, Pablo Bechi, European Hospital, Rome, Italy and others)

11. Pepsin as a Marker of Extraesophageal Reflux;pp. 115-122
(Tina L. Samuels, Nikki Johnston, Medical College of Wisconsin, Milwaukee,USA)

12. Lifestyle Modifications for Reflux;123-130
(Catherine J. Rees, Wake Forest University School of Medicine)

13. Medical Treatment of Laryngopharyngeal Reflux Using Proton Pump Inhibitors;pp. 131-143
(Hans T. Carlson, Paul M. Weinberger, and Gregory N. Postma, Medical College of Georgia, USA)

14. Alginate in the Treatment of Extra-Esophageal Reflux;pp. 145-168 (Vicki Strugala and Peter W. Dettmar, Technostics Ltd. The Deep Business Centre, Kingston Upon Hull, UK)

15. Surgical Management of Extra-Esophageal Reflux;pp. 157-164
(Yong Kwon, Roger P. Tatum and Carlos A. Pellegrini, University of Washington, Seattle,USA)

16. Antireflux Therapy for Patients with Extraesophageal Reflux;pp. 165-181
(Shahin Ayazi and Tom R. DeMeester, Keck School of Medicine, University of Southern California, Los Angeles, USA)

17. Non-Erosive Reflux Disease (NERD). Pathophysiologic, Diagnostic, and Therapeutic Issues;pp. 183-201,
(Gregory S. Riggs, John D. Long, Wake Forest University School of Medicine, Winston-Salem and others)

18. Role of Gastro-Esophageal Reflux and Aspiration of Non-Acidic Gastric Components in the Pathophysiology of Respiratory Disease;pp. 203-215
(Veerle Mertens, Kathleen Blondeau, Ans Pauwels,Ricard Farre, Lieven Dupont and Daniel Sifrim, Center for Gastroenterological Research, KULeuven, Belgium and others)

19. Reflux in Children;217-227
(Tobias G. Wenzl,Universitatsklinikum der RWTH, Aachem, Deutschland)

20. Reflux in Gastroenterology: Pediatric Research;pp. 229-247 (Neelesh Tipnis,Steven Werlin, Medical College of Wisconsin, Milwaukee, USA and others)

Reflux in Otolaryngology

21. Adult Clinical Laryngopharyngeal Reflux;pp. 249-256
(Riitta Möller, Karolinska University Hospital, Stockholm, Sweden)

22. The Role of Reflux in the Development of Laryngeal Cancer;pp. 257-267
(Seth Lieberman and Milan R. Amin, New York University School of Medicine, New York, NY USA)

23. Gastroesophageal Reflux and Laryngotracheal Stenosis;pp. 269-275 (Joel H. Blumin and Robert J. Toohill,Medical College of Wisconsin,USA)

24. Chronic Sinusitis and Gastroesophageal Reflux - Are They Related ;pp. 277-282
(Todd A. Loehrl, VA Medical Center, Medical College of Wisconsin, Milwaukee, USA)

25. The Relationship of Reflux and Sleep Disorders;pp. 283-295
(B. Tucker Woodson and Peter D. O’Connor,Sleep Medicine, Dept. of Otolaryngology and Communications Sciences, Milwaukee, Wisconsin, USA and others)

26. The Lower Esophageal Sphincter and Its Relationship with the Larynx;pp. 297-305
(Albert L. Merati, School of Medicine, University of Washington, Seattle,USA)

27. Non-Gastric Proton Pumps as an Adjunctive Mechanism for Acid Secretion;pp. 307-319
(Kenneth W. Altman, William A. Paradise, Benjamin Vesper, and James A. Radosevich, Mt. Sinai School of Medicine, New York, NY,USA and others)

28. Laryngeal Immunology and Extra-Esophageal Reflux;pp. 321-333 (Paul Weinberger and Martin Birchal, Medical College of Georgia, Augusta, USA and others)

29. Novel Drug Targets for Reflux Disease;pp. 335-345
(Nikki Johnston, Medical College of Wisconsin, Milwaukee,USA)

30. Extra-esophageal Reflux in Children;pp. 347-357
(David J. Brown and Joseph E. Kerschner, Medical College of Wisconsin, Milwaukee,USA)

31. Pediatric Research;pp. 359-376
(Dana Thompson, Mayo Clinic College of Medicine, Rochester,Minnesota,USA)

32. Airway Reflux: Who Recognizes Cinderella?;pp. 377-382
(Alyn Morice, Castle Hill Hospital, Cottingham,East Yorkshire.HU165JQ)

33. Mechanisms of Interactions Between the Esophagus and the Lung;pp. 383-395 (Susan M. Harding, University of Alabama, Birmingham,USA)

34. The Challenge of Reflux-Cough;pp. 397-403
(Amit S. Patel and Surinder S. Birring)

35. Altered Sensitivity of the Upper Airway – Data using Animal Models;pp. 405-422
(Brendan Canning, Marian Kollarik, Johns Hopkins Asthma and Allergy Center,Baltimore, MD,USA)

36. The Role of Altered Upper Airway Sensitivity in Respiratory Disease: Evidence from Human Studies;pp. 423-235
(Lorcan P.A. McGarvey, Sin Y. Phua, BSp Thy (Hons), Alvin J. Ing, The Queen's University of Belfast, N. Ireland and others)

37. Respiratory Disease Due to Extra-Esophageal Reflux in Children;pp. 437-455
Queen's University Belfast and Royal Belfast Hospital for Sick Children, UK)

38. Reflux and Pulmonary Disease: The Pediatric Perspective;pp. 457-473
(Rachel Rosen, and Samuel Nurko, Children's Hospital Boston, MA, USA)

39. Laryngopharyngeal Reflux and Voice Disorders;pp. 475-493
(Robert T. Sataloff, Reena Guptaand Mary J. Hawkshaw, Drexel University College of Medicine, Philadelphia, PA.,USA )

40. Role of Reflux in Speech Language Pathology;pp. 495-503
(Susan L. Thibeault, auniversity of Wisconsin, Madison, USA)

Index pp.505-530

      Digestive Diseases - Research and Clinical Developments
   Binding: Hardcover
   Pub. Date: 2011 - 2nd quarter
   Pages: pp.530
   ISBN: 978-1-61668-177-7
   Status: AV
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Effects, Diagnosis and Management of Extra-Esophageal Reflux