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Malignant Nasopharyngeal Tumors in Children $100.00
Authors:  Marie-Eve Rouge, Hervé Brisse, Sylvie Helfre, Natacha Teissier, Paul Freneaux and Daniel Orbachi
Abstract:
Primary malignant nasopharyngeal tumors are relatively rare in children. The most frequent childhood neoplasms in this region are rhabdomyosarcoma (RMS), Undifferentiated Carcinoma of Nasopharyngeal Type (UCNT) and Non-Hodgkin‘s Lymphoma (NHL). Children with these tumors usually present with nasal obstruction, headache, nasal swelling or cervical node involvement. The nasopharyngeal mass may be discovered during an ear, nose and throat examination and is confirmed by medical imaging. The diagnosis may be suspected on fine needle aspiration and is confirmed by biopsy of the nasopharyngeal mass or cervical lymph node.
The treatments and prognoses differ for these 3 types of tumors. The objective of this paper is to review the diagnostic and therapeutic approach to childhood malignant nasopharyngeal tumors such as RMS, NHL and UCNT. The authors also review the known prognostic factors of these diseases in order to discuss treatment adaptation, especially in young children. 


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Malignant Nasopharyngeal Tumors in Children