Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
  Top » Catalog » Books » Biology » Cell Biology » Chemokines: Types, Functions, and Structural Characteristics Chapters » My Account  |  Cart Contents  |  Checkout   
Quick Find
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
Doxycycline: Medical Uses and Effects
Shopping Cart more
0 items
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Notifications more
NotificationsNotify me of updates to Chemokines in Teleost Fish Species pp. 73-88
Tell A Friend
Tell someone you know about this product.
Chemokines in Teleost Fish Species pp. 73-88 $0.00
Authors:  Carolina Tafalla, Alí Alejo, Centro de Investigación en Sanidad Animal (CISA-INIA), Valdeolmos, Madrid, Spain
Chemokines are chemoattractant cytokines defined by the presence of four conserved cysteine residues which in mammals can be divided into four subfamilies depending on the arrangement of the first two conserved cysteines in their sequence: CXC (), CC (), C and CX3C classes.
Evolutionarily, fish can be considered as an intermediate step between species which possess only innate immunity (invertebrates) and species which depend greatly on their adaptive immunity such as mammals. Therefore, the functionality of their different immune cell types and molecules is sometimes also intermediate between innate and adaptive responses. The first chemokine gene identified in fish was an interleukin 8 (IL-8) homologue characterized in lamprey (Lampetra fluviatilis) in 1999. Since then, many different chemokine genes have been identified in several fish species evidencing the great differences that exist between mammalian and fish chemokines. In this group of animals, only chemokines belonging to CC and CXC classes have been identified in most species, while in zebrafish (Danio rerio) some C chemokines have been reported, as well as a new CX group with four members of unknown function. Moreover, extensive intrachromosomal gene duplications have considerably increased the number of genes in most species, and while twenty-eight CC members have been identified in mammals, at least eighty-one CC chemokine genes are present in zebrafish. The role of these molecules in homeostasis and immune response remains largely unknown. 

Available Options:

  Open Access item.
  Click below PDF icon for free download.


This is an Open Access item. Click above PDF icon for free download.
Special Focus Titles
01.Violent Communication and Bullying in Early Childhood Education
02.Cultural Considerations in Intervention with Women and Children Exposed to Intimate Partner Violence
03.Chronic Disease and Disability: The Pediatric Lung
04.Fruit and Vegetable Consumption and Health: New Research
05.Fire and the Sword: Understanding the Impact and Challenge of Organized Islamism. Volume 2

Nova Science Publishers
© Copyright 2004 - 2020

Chemokines in Teleost Fish Species pp. 73-88