Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
            
  Top » Catalog » Books » Biology » Cell Biology » Chemokines: Types, Functions, and Structural Characteristics Chapters » My Account  |  Cart Contents  |  Checkout   
Quick Find
  
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
_Cancer Research Journal - This journal ceased publication after 4#4 (2010). Back Issues are available.
$195.00
Shopping Cart more
0 items
Information
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Notifications more
NotificationsNotify me of updates to Gene Regulation and Expression of Chemokines in Response to Bacterial Enterotoxins pp. 89-110
Tell A Friend
 
Tell someone you know about this product.
Gene Regulation and Expression of Chemokines in Response to Bacterial Enterotoxins pp. 89-110 $100.00
Authors:  Jung Mogg Kim, Department of Microbiology, Hanyang University College of Medicine, Seoul, South Korea
Abstract:
Bacterial enterotoxins are proteins released by specific bacterial organisms in the intestine and are chromosomally encoded exotoxins. The first host cells that enterotoxins interact with are intestinal epithelial cells, after which mucosal inflammatory signals are initiated. Characteristic features of inflammatory signals are the chemokine expression, leading to the migration of inflammatory cells into intestinal mucosa. Several microbial organisms produce the enterotoxin to create such an effect. These bacteria contain enterotoxigenic Bacteroides fragilis, Clostridium difficile and Staphylococcus aureus. This chapter will focus on the impact of bacterial enterotoxins on the gene regulation and expression of chemokines in intestinal epithelial cells.
Enterotoxins produced from those bacteria up-regulate the expression of CXC and CC chemokines. The kinetics of each chemokine expression is different. For example, expression of the CXC chemokines, including IL-8 and growth-related oncogene (GRO)-, and the CC chemokines, including monocyte chemoattractant protein (MCP)-1, increases during the relatively early period after stimulation with C. difficile enterotoxin (toxin A) and B. fragilis enterotoxin. In contrast, expression of neutrophil activating protein-78 (ENA-78) is delayed. These findings suggest that the chemokines can contribute to the infiltration of inflammatory cells in the underlying infected intestinal mucosa. 


Available Options:
Version:
This Item Is Currently Unavailable.
Special Focus Titles
01.Violent Communication and Bullying in Early Childhood Education
02.Cultural Considerations in Intervention with Women and Children Exposed to Intimate Partner Violence
03.Chronic Disease and Disability: The Pediatric Lung
04.Fruit and Vegetable Consumption and Health: New Research
05.Fire and the Sword: Understanding the Impact and Challenge of Organized Islamism. Volume 2

Nova Science Publishers
© Copyright 2004 - 2020

Gene Regulation and Expression of Chemokines in Response to Bacterial Enterotoxins pp. 89-110