Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
            
  Top » Catalog » Books » Biology » Biology - General » Advances in Medicine and Biology. Volume 8 Chapters » My Account  |  Cart Contents  |  Checkout   
Quick Find
  
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
Fetal Alcohol Syndrome: Recognition, Differential Diagnosis and Long-Term Effects
$82.00
Shopping Cart more
0 items
Information
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Notifications more
NotificationsNotify me of updates to Epigenetic Factors in Hereditary Breast Cancer, pp. 211-229
Tell A Friend
 
Tell someone you know about this product.
Epigenetic Factors in Hereditary Breast Cancer, pp. 211-229 $100.00
Authors:  Matilde Pensabene, Caterina Condello, Sabino De Placido, Alma Contegiacomo, Stefano Pepe, Clinical Unit of “Screening and Follow-Up for Hereditary and Familial Cancers” at the Department of “Molecular and Clinical Endocrinology and Oncology”, Azienda Ospedaliera Universitaria (AOU) “Federico II” in Naples, Italy, and others
Abstract:
Germline mutations in BRCA1 and BRCA2 genes confer high risk of developing breast and ovarian cancer. Among individuals and families there is a strong cancer risk variation both for age of onset and for sites involved. The interaction among genetic and non genetic factors can explain differences in penetrance. There are several potential causes of variation. Among genetic causes the type and position of the mutation, allelic variations as well as mutation in other genes, known as modifying genes, can impact on risk variation and different correlation among genotype-phenotype. Different variables such as micro and macro-environmental factors (i.e., reproductive, hormonal anthropometric, dietary and environmental exposure factors) can also impact on cancer development in hereditary breast and/or ovarian cancer syndrome (HBOC). All together these factors can play the role of epigenetic factors that could modify breast cancer risk.
Several case-control studies have been performed on the relation between breast cancer risk in BRCA1 and BRCA2 mutation carrier and other risk factors already evaluated for sporadic breast cancer. 


Available Options:
Version:
This Item Is Currently Unavailable.
Special Focus Titles
01.Violent Communication and Bullying in Early Childhood Education
02.Cultural Considerations in Intervention with Women and Children Exposed to Intimate Partner Violence
03.Chronic Disease and Disability: The Pediatric Lung
04.Fruit and Vegetable Consumption and Health: New Research
05.Fire and the Sword: Understanding the Impact and Challenge of Organized Islamism. Volume 2

Nova Science Publishers
© Copyright 2004 - 2020

Epigenetic Factors in Hereditary Breast Cancer, pp. 211-229