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01.Sickle Cell Hemoglobinopathy And Sudden Death (pp. 125-130)
02.Stroke In Sickle Cell Anemia In The Mid-Southern Region Of Turkey (pp. 59-67)
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Stroke In Sickle Cell Anemia In The Mid-Southern Region Of Turkey (pp. 59-67) $25.00
Authors:  Kilinç, Yurdanur; Şaşmaz, Ilgen; Antmen, Bülent; Kozanoglu, H. Hayriye; Soyupak, Süreyya; Altunbaşak, Şakir (Çukurova University, Adana, Turkey)
Abstract:
Stroke is one of the most serious complications at crisis period in SCA patients. If it is not prevented in time, various motor and mental problems may appear in these patients. The SCA patients may show clinical patterns as severe or mild courses. If the patient has severe clinical pattern, he or she may have suffered from frequent vaso-occlusive crises, hemolytic, sequestration crisis and cerebrovascular accidents from the early ages of life and may need RBCs transfusions. 320 registered SCA patients with HbSS pattern is in follow-up clinics in Pediatric Hematology Department of Çukurova University. In last ten years, 16 of the patients had suffered from stroke. This conforms 5% of SCA population. This means we have to take care of the SCA patients carefully. The patients ages were between 11 months-17 years, 8 of them were females. In 16 patients, admitted with stroke, hematological and blood chemistry findings was determined. Also, neurological manifestations and findings were evaluated. The radiodiagnostics studies have been done. They were brought to the hospital with paresis, paralysis, confusion, loss of consciousness. They have hospitalized, have had partial exchange transfusions. They are in follow-up if alive and in last five years, we began hydroxyurea in therapy and planned BMT in some cases. The mortality rate from stroke in study group is 2/16 (12.5 %) 


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Stroke In Sickle Cell Anemia In The Mid-Southern Region Of Turkey (pp. 59-67)