Main Fungal Pathogens Causing Infections in Immunocompromised Patients pp. 281-300
Authors: (Amany El Sharif, Department of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, Cairo, Egypt)
Abstract: Fungi are increasingly recognized as major pathogens in critically ill patients. Medically important fungi are included in four groups known as Zygomycota, Basidiomycota, Deuteromycota and Ascomycota. The most frequently isolated fungi in clinical practice are Candida spp.Candida albicans is the most frequent species isolated, but other species nonalbicans Candida (NAC) are progressively detected and isolated. NAC are of special concern, since some are highly virulent and are associated with treatment failure due to reduced susceptibility to antifungal agents. The most frequent filamentous fungi (moulds) caused problems for immunocompromised patients were identified as Aspergillus spp., but Fusarium spp., Scedosporium spp., Penicillium spp., and Zygomycetes are increasingly reported. This chapter shed light on main fungal pathogen frequently isolated from immunocompromised patients with fungal infections.