The Effects of Smoking Cessation: What Happens to our Body after Smoking Cessation? pp. 231-240
Authors: (Wang-Youn Won, Seong-Su Lee, Dai-Jin Kim, Department of Psychiatry, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Republic of Korea, and others)
Abstract: Cigarette smoking is one of the leading causes of premature death and a major risk factor for many disease entities. There is substantial evidence supporting the harmful effects of smoking on the respiratory, cardiovascular, and cerebrovascular systems. Carcinogenesis, vasomotor dysfunction, impaired endothelial-dependent vasodilation, and the modification of lipid profiles are among the harmful effects described. Smoking also has been shown to be associated with insulin resistance, impaired intravascular lipolysis and dyslipidemia. Less is known about metabolic and neurogenic effects of smoking cessation. The objective of this review was to identify the effects of smoking cessation on metabolism including energy, glucose and lipids, markers of neurogenesissuch as the brain-derived neurotrophic factor, nerve growth factor, and various gut hormones and other peptides regulating appetiteincluding ghrelin and leptin. In addition, the hematological changes and hormonal effects,following smoking cessation, were reviewed.