Book Description:
Signal transduction plays a pivotal role in cellular regulation. The second messenger is generated in cells once the first messenger binds to the receptors of plasma membranes. The second messenger, which was found firstly, is cyclic adenosine monophosphate. After that, intracellular calcium ion (Ca2+) has been demonstrated to play a role as a second messenger for hormonal stimulation in cells. The pivotal role of Ca2+ in cellular regulation was established with the finding of calmodulin and protein kinase C that modulate the effect of Ca2+ in the regulation of cellular functions. Calcium signaling is probably the most ubiquitous cellular signal that mediates the action of many hormones, cytokines, and neurotransmitters. This book provides an in depth examination of calcium signaling. (Imprint: Nova)

Table of Contents:
Preface

Chapter 1. Ca2+ Signaling in Lower Eukaryote;pp. 1-36
(I.V. Shemarova)

Chapter 2. The Store-Operated Calcium Entry Pathway;pp. 37-58
(Juan A. Rosado)

Chapter 3. Role of calcium in stress mediated signaling in plants;pp. 59-104
(Cheshta Sharma, Amita Pandey, Girdhar K. Pandey)

Chapter 4. Calmodulin signaling inside-out: Intracellular and extracellular calmodulin and its interaction with a matricellular cysteine-rich calmodulin-binding protein;pp. 105-118
(Danton H. O’Day, Robert Huber, Andres Suarez)

Chapter 5. A tale of three proteins: The nucleolar calmodulin-binding protein nucleomorphin and its binding partners calcium-binding protein 4a and puromycin-sensitive aminopeptidase;pp. 119-130
(Danton H. O’Day, Andrew Catalano, Yekaterina Poloz)

Chapter 6. Insights into the role of intracellular Ca2+ concentration changes during in vitro chondrogenesis;pp. 131-147
(Csaba Matta, János Fodor, Tamás Juhász, Róza Zákány)

Chapter 7. Cav2.1 channelopathies and mouse genetic approaches for
investigating Cav2.1 channel function and dysfunction;pp. 149-158
(Eiki Takahashi)

Chapter 8. Regucalcin: Role as a suppressor protein in calcium signaling;pp. 159-214
(Masayoshi Yamaguchi)

Chapter 9. Calcium ([Ca2+]i ) signaling as a key-target for cancer treatment;pp. 215-220
(Ana-Maria Florea, Dietrich Büsselberg)

Index