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01.Vertebral Compression Fractures from Spinal Metastases: Imaging and Application of Kyphoplasty and Vertebroplasty (p. 63-71)
02.Bone Metastases and Quality of Life (p. 117-131)
03.Defining Oncologic Spinal Instability (p. 55-61)
04.Bisphosphonates in the Management of Bone Metastases (p. 91-97)
05.Evaluation of Photodynamic Therapy as Treatment for Spinal Metastases (p. 83-91)
06.Less Invasive Surgical Approaches for Spine Metastases (p. 73-81)
07.Management of Malignant Spinal Cord Compression (p. 43-53)
08.Palliative Radiotherapy of Bone Metastases and Pain Flare (p. 105-115)
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Management of Malignant Spinal Cord Compression (p. 43-53) $45.00
Authors:  Gunita Mitera, Arjun Sahgal, Normand Laperriere and Andrew Loblaw
Abstract:
Malignant spinal cord compression (MSCC) may present as either an extradural (MESCC) or intradural (ICC) lesion, with the majority presenting as MESCC. The clinical incidence of MSCC is approximately 2.5-10% for all cancer patients. While a patientís prognostic outlook is between 3-6 months, good prognostic factors for survival include solitary skeletal metastases, the absence of visceral or brain metastases, and a long interval between cancer diagnosis and MSCC. The goal of treatment should be palliation of pain, neurological recovery, and quality of life (QOL). However, it is important to individualize each patientís treatment regime according to their prognosis and possible outcome. Complications of this illness may result in irreversible pain, physical and neurological deficit, hence, prioritizing this as one of few radiation oncology emergencies. This chapter discusses the management of MSCC with an emphasis on research conducted by investigators within the University of Toronto. This discussion will include incidence, functional outcomes, evidence guided treatment recommendations, novel management strategies, and QOL issues for both MESCC and ICC. The paper concludes with insight into future research. 


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Management of Malignant Spinal Cord Compression (p. 43-53)