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Techniques for Presurgical Exploration of Language Lateralization in Children, pp. 87-110 $100.00
Authors:  (Anne Gallagher, Renée Béland, Maryse Lassonde, Centre de Recherche en Neuropsychologie et Cognition, Université de Montréal, Montreal, Quebec, Canada, and others)
Some patients with medically intractable epilepsy are candidates for neurosurgery. To minimize cognitive sequelae, an exhaustive presurgical assessment is required. Investigation of language lateralization is an important part of the presurgical work-up, especially because epileptic patients frequently present atypical language dominance. Among the procedures used to investigate language lateralization, the Intracarotid Amobarbital Test (IAT) is still the most widely used. However, it has many limitations, in particular the fact that it is invasive and may be traumatic, especially for children. To overcome these limitations, neuroimaging techniques, such as positron emission tomography, single-photon emission computed tomography, functional magnetic resonance imaging, near infrared spectroscopy, magnetoencephalography, functional transcranial Doppler monitoring, and repetitive transcranial magnetic stimulation, are currently used as less invasive alternatives. Nevertheless, although these techniques present many advantages, they have limitations, an important one being that very few can be used with young children. The aim of this review is to describe traditional and innovative language lateralization techniques and to evaluate their applicability to a pediatric population. 

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Techniques for Presurgical Exploration of Language Lateralization in Children, pp. 87-110